Drew Hannaman
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Explore the profile of Drew Hannaman including associated specialties, affiliations and a list of published articles.
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59
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1242
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Recent Articles
1.
Kalams S, Felber B, Mullins J, Scott H, Allen M, De Rosa S, et al.
JCI Insight
. 2024 Aug;
9(18).
PMID: 39088271
BACKGROUNDAn HIV-1 DNA vaccine composed of 7 highly conserved, structurally important elements (conserved elements, CE) of p24Gag was tested in a phase I randomized, double-blind clinical trial (HVTN 119, NCT03181789)...
2.
Jacobson J, Felber B, Chen H, Pavlakis G, Mullins J, De Rosa S, et al.
AIDS
. 2023 Dec;
38(7):963-973.
PMID: 38051788
Objective: The primary objective of the study was to assess the immunogenicity of an HIV-1 Gag conserved element DNA vaccine (p24CE DNA) in people with HIV (PWH) receiving suppressive antiretroviral...
3.
Wilson G, Rodriguez B, Li S, Allen M, Frank I, Rudnicki E, et al.
Vaccine
. 2023 Mar;
41(16):2696-2706.
PMID: 36935288
Background: HIV subtypes B and C together account for around 60% of HIV-1 cases worldwide. We evaluated the safety and immunogenicity of a subtype B DNA vaccine prime followed by...
4.
Mpendo J, Mutua G, Nanvubya A, Anzala O, Nyombayire J, Karita E, et al.
PLoS One
. 2020 May;
15(5):e0233151.
PMID: 32469893
Introduction: Intramuscular electroporation (IM/EP) is a vaccine delivery technique that improves the immunogenicity of DNA vaccines. We evaluated the acceptability and tolerability of electroporation among healthy African study participants. Methods:...
5.
Haidari G, Day S, Wood M, Ridgers H, Cope A, Fleck S, et al.
Front Immunol
. 2020 Jan;
10:2911.
PMID: 31921170
Previous studies have shown targeting different tissues via the transcutaneous (TC) and intramuscular injection (IM) with or without electroporation (EP) has the potential to trigger immune responses to DNA vaccination....
6.
Hess R, Storcksdieck Genannt Bonsmann M, Lapuente D, Maaske A, Kirschning C, Ruland J, et al.
Viruses
. 2019 Feb;
11(2).
PMID: 30781796
The envelope protein (Env) is the only surface protein of the human immunodeficiency virus (HIV) and as such the exclusive target for protective antibody responses. Experimental evidences from mouse models...
7.
Elizaga M, Li S, Kochar N, Wilson G, Allen M, Tieu H, et al.
PLoS One
. 2018 Sep;
13(9):e0202753.
PMID: 30235286
Background: The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations. The objective of this study...
8.
Cheeseman H, Day S, McFarlane L, Fleck S, Miller A, Cole T, et al.
Hum Gene Ther
. 2018 Jul;
29(9):1011-1028.
PMID: 30027768
Intradermal (i.d.) and intramuscular (i.m.) injections when administered with or without electroporation (EP) have the potential to tailor the immune response to DNA vaccination. This Phase I randomized controlled clinical...
9.
Dupuy L, Richards M, Livingston B, Hannaman D, Schmaljohn C
J Immunol Res
. 2018 Jul;
2018:8521060.
PMID: 29967804
There remains a need for vaccines that can safely and effectively protect against the biological threat agents Venezuelan (VEEV), western (WEEV), and eastern (EEEV) equine encephalitis virus. Previously, we demonstrated...
10.
Patel P, Ottensmeier C, Mulatero C, Lorigan P, Plummer R, Pandha H, et al.
Oncoimmunology
. 2018 Jun;
7(6):e1433516.
PMID: 29872563
A DNA vaccine, SCIB1, incorporating two CD8 and two CD4 epitopes from TRP-2/gp100 was evaluated in patients with metastatic melanoma. Each patient received SCIB1 via intramuscular injection with electroporation. The...