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Leopoldo Aguilera-Aguirre

Explore the profile of Leopoldo Aguilera-Aguirre including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1155
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Recent Articles
1.
van Tol S, Kalveram B, Ilinykh P, Ronk A, Huang K, Aguilera-Aguirre L, et al.
PLoS Pathog . 2022 May; 18(5):e1010532. PMID: 35533195
Ebola virus (EBOV) VP35 is a polyfunctional protein involved in viral genome packaging, viral polymerase function, and host immune antagonism. The mechanisms regulating VP35's engagement in different functions are not...
2.
Hage A, Bharaj P, van Tol S, Giraldo M, Gonzalez-Orozco M, Valerdi K, et al.
Cell Rep . 2022 Mar; 38(10):110434. PMID: 35263596
Type I interferons (IFN-I) are essential to establish antiviral innate immunity. Unanchored (or free) polyubiquitin (poly-Ub) has been shown to regulate IFN-I responses. However, few unanchored poly-Ub interactors are known....
3.
Giraldo M, Xia H, Aguilera-Aguirre L, Hage A, van Tol S, Shan C, et al.
Nature . 2020 Jul; 585(7825):414-419. PMID: 32641828
Zika virus (ZIKV) belongs to the family Flaviviridae, and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological disorders and replicates...
4.
Sreedhar A, Aguilera-Aguirre L, Singh K
Cell Death Dis . 2020 Jun; 11(6):444. PMID: 32518230
The skin is a high turnover organ, and its constant renewal depends on the rapid proliferation of its progenitor cells. The energy requirement for these metabolically active cells is met...
5.
Hosoki K, Jaruga P, Itazawa T, Aguilera-Aguirre L, Coskun E, Hazra T, et al.
Clin Exp Allergy . 2018 Sep; 48(12):1676-1687. PMID: 30244512
Background: Ragweed pollen extract (RWPE) induces TLR4-NFκB-CXCL-dependent recruitment of ROS-generating neutrophils to the airway and OGG1 DNA glycosylase-dependent excision of oxidatively induced 8-OH-Gua DNA base lesions from the airway epithelial...
6.
Hao W, Qi T, Pan L, Wang R, Zhu B, Aguilera-Aguirre L, et al.
Redox Biol . 2018 Jun; 18:43-53. PMID: 29940424
8-Oxoguanine DNA glycosylase 1 (OGG1) initiates the base excision repair pathway by removing one of the most abundant DNA lesions, 8-oxo-7,8-dihydroguanine (8-oxoG). Recent data showed that 8-oxoG not only is...
7.
Richardson L, Dixon C, Aguilera-Aguirre L, Menon R
Biol Reprod . 2018 Jun; 99(5):1100-1112. PMID: 29893818
Term and preterm parturition are associated with oxidative stress (OS)-induced p38 mitogen-activated protein kinase (p38MAPK)-mediated fetal tissue (amniochorion) senescence. p38MAPK activation is a complex cell- and stimulant-dependent process. Two independent...
8.
Aguilera-Aguirre L, Hao W, Pan L, Li X, Saavedra-Molina A, Bacsi A, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 Aug; 313(6):L1058-L1068. PMID: 28798252
A mucosal oxidative burst is a hallmark response to pollen exposure that promotes allergic inflammatory responses. Reactive species constituents of oxidative stress signal via the modification of cellular molecules including...
9.
Hosoki K, Redding D, Itazawa T, Chakraborty A, Tapryal N, Qian S, et al.
J Allergy Clin Immunol . 2017 Jun; 140(5):1436-1439.e5. PMID: 28583369
No abstract available.
10.
Garcia N, Zazueta C, Aguilera-Aguirre L
Oxid Med Cell Longev . 2017 May; 2017:5853238. PMID: 28536646
No abstract available.