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Leonard B Bacharier

Explore the profile of Leonard B Bacharier including associated specialties, affiliations and a list of published articles. Areas
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Articles 291
Citations 7811
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Recent Articles
1.
Bacharier L
Respir Care . 2025 Mar; PMID: 40040424
Children with severe asthma incur substantial disease-related morbidity. Despite treatment with inhaled corticosteroids and additional controller medications, many patients continue to experience recurrent exacerbations, impaired lung function, and diminished quality...
2.
Thompson E, Zhong X, Carbonetto P, Morin A, Willwerscheid J, Visness C, et al.
medRxiv . 2025 Mar; PMID: 40034775
Background: Asthma is the most common chronic respiratory disease in children, but little is known about genetic contributions to its underlying endotypes. To address this gap, we studied the methylome,...
3.
Gaberino C, Altman M, Gill M, Bacharier L, Gruchalla R, OConnor G, et al.
J Allergy Clin Immunol . 2025 Jan; PMID: 39788435
Background: Determining why some upper respiratory illnesses provoke asthma exacerbations remains an unmet need. Objective: We sought to identify transcriptome-wide gene expression changes associated with colds that progress to exacerbation....
4.
Togias A, Gergen P, Liu A, Kim H, Wood R, OConnor G, et al.
J Allergy Clin Immunol . 2025 Jan; PMID: 39755282
Background: Rhinoconjunctivitis phenotypes are conventionally described on the basis of symptom severity, duration and seasonality, and aeroallergen sensitization. It is not known whether these phenotypes fully reflect the patterns of...
5.
Brunwasser S, Gebretsadik T, Satish A, Cole J, Dupont W, Joseph C, et al.
Prev Med Rep . 2024 Dec; 49:102936. PMID: 39697187
Objective: Understanding compliance with COVID-19 mitigation recommendations is critical for informing efforts to contain future infectious disease outbreaks. This study tested the hypothesis that higher levels of worry about COVID-19...
6.
Non A, Li X, Jones M, Oken E, Hartert T, Schoettler N, et al.
Am J Respir Crit Care Med . 2024 Dec; 211(3):464-476. PMID: 39642347
Race-based estimates of pulmonary function in children could influence the evaluation of asthma in children from racial and ethnic minoritized backgrounds. To determine if race-neutral (Global Lung Function Initiative [GLI]-Global)...
7.
Lanz M, Chipps B, Zeiger R, Bacharier L, Guilbert T, Murphy K, et al.
Ann Allergy Asthma Immunol . 2024 Nov; 134(2):198-208.e2. PMID: 39615584
Background: Asthma in children is a leading cause of missed school days, emergency department visits, and hospitalizations. Approximately 40% of children with asthma experience uncontrolled disease and annual exacerbations. There...
8.
Jackson D, Hamelmann E, Roberts G, Bacharier L, Xia C, Gall R, et al.
J Allergy Clin Immunol Pract . 2024 Nov; 13(3):568-575. PMID: 39613097
Background: Elevated blood or tissue eosinophils are considered to characterize type 2 inflammation in children with asthma and are associated with increased exacerbation rates and worse asthma control. Dupilumab, a...
9.
Rosas-Salazar C, Bacharier L, Hartert T
N Engl J Med . 2024 Nov; 391(21):2058-2059. PMID: 39602640
No abstract available.
10.
Rosser F, Han Y, Forno E, Guilbert T, Bacharier L, Phipatanakul W, et al.
Am J Respir Crit Care Med . 2024 Nov; 211(2):266-268. PMID: 39485865
No abstract available.