George T OConnor
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Explore the profile of George T OConnor including associated specialties, affiliations and a list of published articles.
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253
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11822
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Recent Articles
1.
Thompson E, Zhong X, Carbonetto P, Morin A, Willwerscheid J, Visness C, et al.
medRxiv
. 2025 Mar;
PMID: 40034775
Background: Asthma is the most common chronic respiratory disease in children, but little is known about genetic contributions to its underlying endotypes. To address this gap, we studied the methylome,...
2.
Oelsner E, Krishnaswamy A, Rustamov R, Balte P, Ali T, Allen N, et al.
PLoS One
. 2025 Feb;
20(2):e0316198.
PMID: 39928595
Rationale: Robust COVID-19 outcomes classification is important for ongoing epidemiology research on acute and post-acute COVID-19 conditions. Protocolized medical record review is an established method to validate endpoints for clinical...
3.
Zhang J, Hobbs B, Silverman E, Sparrow D, Ortega V, Xu H, et al.
JAMA
. 2025 Jan;
333(9):784-792.
PMID: 39841442
Importance: Chronic obstructive pulmonary disease (COPD) is often undiagnosed. Although genetic risk plays a significant role in COPD susceptibility, its utility in guiding spirometry testing and identifying undiagnosed cases is...
4.
Gaberino C, Altman M, Gill M, Bacharier L, Gruchalla R, OConnor G, et al.
J Allergy Clin Immunol
. 2025 Jan;
PMID: 39788435
Background: Determining why some upper respiratory illnesses provoke asthma exacerbations remains an unmet need. Objective: We sought to identify transcriptome-wide gene expression changes associated with colds that progress to exacerbation....
5.
Togias A, Gergen P, Liu A, Kim H, Wood R, OConnor G, et al.
J Allergy Clin Immunol
. 2025 Jan;
PMID: 39755282
Background: Rhinoconjunctivitis phenotypes are conventionally described on the basis of symptom severity, duration and seasonality, and aeroallergen sensitization. It is not known whether these phenotypes fully reflect the patterns of...
6.
Brunwasser S, Gebretsadik T, Satish A, Cole J, Dupont W, Joseph C, et al.
Prev Med Rep
. 2024 Dec;
49:102936.
PMID: 39697187
Objective: Understanding compliance with COVID-19 mitigation recommendations is critical for informing efforts to contain future infectious disease outbreaks. This study tested the hypothesis that higher levels of worry about COVID-19...
7.
Bhatt S, Wu C, Sun Y, Balte P, Schwartz J, Divo M, et al.
Ann Am Thorac Soc
. 2024 Oct;
22(3):359-366.
PMID: 39447115
Chronic lung diseases are associated with increased risk of mortality due to coronary heart disease (CHD). Nonetheless, the population attributable fraction (PAF) of lung function impairment relative to other established...
8.
Sangani R, Lee M, Xu H, Dupuis J, OConnor G
CHEST Pulm
. 2024 Oct;
2(3).
PMID: 39421758
Background: Lung function declines over the course of adulthood; however, a consensus on the normal range of decline in an individual's lung function is lacking. Research Question: What is the...
9.
Abdalla M, Elalami R, Cho M, OConnor G, Rice M, Horowitz M, et al.
J Clin Exp Pathol
. 2024 Oct;
14(3).
PMID: 39360267
Introduction: Mucus pathology plays a critical role in airway diseases like Chronic Bronchitis (CB) and Chronic Obstructive Pulmonary Disease (COPD). Up to 32% of community-living persons report clinical manifestations of...
10.
Ramratnam S, Johnson M, Visness C, Calatroni A, Altman M, Janczyk T, et al.
J Allergy Clin Immunol
. 2024 Sep;
155(2):547-556.
PMID: 39307288
Background: Chronic rhinitis symptoms cause significant health burden among children and can have a heterogeneous presentation. Defining phenotypes of childhood chronic rhinitis and associated pathobiology may lead to prevention or...