Leon Schurgers
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Explore the profile of Leon Schurgers including associated specialties, affiliations and a list of published articles.
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57
Citations
1728
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Recent Articles
1.
de la Puente-Secades S, Mikolajetz D, Gayrard N, Hermann J, Jankowski V, Bhargava S, et al.
Cardiovasc Res
. 2025 Mar;
PMID: 40042167
Aims: Patients with chronic kidney disease (CKD) show a high risk of cardiovascular diseases, predominantly caused by accelerated vascular calcification. Vascular calcification is a highly regulated process with no current...
2.
Negm S, Wolf M, Craveiro R, Schurgers L, Jankowski J, Schneider R, et al.
BMC Oral Health
. 2025 Feb;
25(1):226.
PMID: 39939842
Objective: Resveratrol is a plant polyphenol known for its anti-inflammatory and pro-regenerative properties. These could be beneficial in controlling potential side effects of orthodontic treatment, such as apical root resorption....
3.
Habibi A, Ruf W, Schurgers L
Cell Commun Signal
. 2025 Jan;
23(1):57.
PMID: 39891111
Coagulation factors are responsible for blood clot formation yet have also non-canonical functions as signalling molecules. In this context, they can activate protease-activated receptors (PARs) ubiquitously expressed in the vasculature....
4.
Marreiros C, Viegas C, Guedes A, Paula Silva A, Aguas A, Faisca M, et al.
J Clin Med
. 2024 Dec;
13(23).
PMID: 39685887
: Vascular calcification (VC) is a crucial risk factor for cardiovascular diseases (CVD), particularly in chronic kidney disease (CKD) populations. However, the specific relationship between VC and end-stage renal disease...
5.
Parikh S, Wehrens A, Giudici A, Ganizada B, Saraber P, Schurgers L, et al.
J Biomech
. 2024 Dec;
179():112447.
PMID: 39644801
Local biaxial deformation plays a pivotal role in evaluating the tissue state of the ascending aorta and in driving intramural cell-mediated tissue remodeling. Unfortunately, the absence of anatomical markers on...
6.
Medina I, Wieland E, Temmerman L, Otten J, Bermudez B, Bot I, et al.
Eur J Immunol
. 2024 Sep;
54(11):e2350943.
PMID: 39233527
Macrophage infiltration and accumulation in the atherosclerotic lesion are associated with plaque progression and instability. Depletion of macrophages from the lesion might provide valuable insights into plaque stabilization processes. Therefore,...
7.
Pinto E, Viegas C, Martins P, Marreiros C, Nascimento T, Schurgers L, et al.
Nutrients
. 2024 Apr;
16(8).
PMID: 38674788
The Mediterranean diet (MD) is associated with improved longevity and the prevention and management of chronic inflammatory diseases (CIDs). Vitamin K, which is present in MD core components such as...
8.
Haroon S, Davenport A, Ling L, Tai B, Teo L, Schurgers L, et al.
Kidney Int Rep
. 2023 Sep;
8(9):1741-1751.
PMID: 37705910
Introduction: Vitamin K deficiency among patients on hemodialysis (HD) affects the function of matrix GLA protein (MGP), a potent vitamin K-dependent inhibitor of vascular calcification (VC). Methods: We conducted a...
9.
Pinto E, Viegas C, Martins P, Nascimento T, Schurgers L, Simes D
Nutrients
. 2023 Jul;
15(13).
PMID: 37447338
Vitamin K is a multifunctional micronutrient essential for human health, and deficiency has been linked to multiple pathological conditions. In this study, we aimed to develop and validate a new...
10.
Panagiotou N, McGuinness D, Jaminon A, Mees B, Selman C, Schurgers L, et al.
Cells
. 2023 Jul;
12(13).
PMID: 37443741
Extracellular vesicles (EVs), comprising microvesicles (MVs) and exosomes (Exos), are membranous vesicles secreted by cells which mediate the repair of cellular and tissue damage via paracrine mechanisms. The action of...