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Leon Bernal-Mizrachi

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Recent Articles
11.
Qu C, Kunkalla K, Vaghefi A, Frederiksen J, Liu Y, Chapman J, et al.
Cancer Lett . 2018 Aug; 436:149-158. PMID: 30165192
Tumor necrosis factor receptor-associated factor 6 (TRAF6), an (K63) E3-ligase, plays a role in many biological processes and its activity is relevant in diffuse large B cell lymphoma (DLBCL) biology....
12.
Redelico T, Walton S, Lafollette J, Adams Curry M, Bernal-Mizrachi L
J Oncol Pract . 2018 May; 14(7):e446-e450. PMID: 29813011
Introduction: Oral anticancer medications (OAMs) offer convenient administration but create new challenges with unique toxicity profiles, specific monitoring parameters and non-continuous dosing schedules. We evaluated provider compliance with US Food...
13.
Reddy A, Zhang J, Davis N, Moffitt A, Love C, Waldrop A, et al.
Cell . 2017 Oct; 171(2):481-494.e15. PMID: 28985567
Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity poses a...
14.
Yun H, Dossul T, Bernal-Mizrachi L, Switchenko J, Ndibe C, Ibraheem A, et al.
J Stem Cell Res Ther . 2017 Oct; 6. PMID: 28966870
Disparities in clinical care have been described for patients with limited insurance coverage or social support. We hypothesized that patients with relapsed Hodgkin lymphoma (HL), non-Hodgkin lymphoma (NHL), or multiple...
15.
McKinney M, Moffitt A, Gaulard P, Travert M, de Leval L, Nicolae A, et al.
Cancer Discov . 2017 Jan; 7(4):369-379. PMID: 28122867
Hepatosplenic T-cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown. Through whole-exome sequencing of 68 HSTLs, we define recurrently mutated driver genes...
16.
Bulka C, Nastoupil L, Koff J, Bernal-Mizrachi L, Ward K, Williams J, et al.
South Med J . 2016 Oct; 109(10):606-614. PMID: 27706495
Objectives: Examining the spatial patterns of diffuse large B-cell lymphoma (DLBCL) incidence and residential proximity to toxic release locations may provide insight regarding environmental and sociodemographic risk factors. Methods: We...
17.
Rand K, Song C, Dean E, Serie D, Curtin K, Sheng X, et al.
Cancer Epidemiol Biomarkers Prev . 2016 Sep; 25(12):1609-1618. PMID: 27587788
Background: Genome-wide association studies (GWAS) in European populations have identified genetic risk variants associated with multiple myeloma. Methods: We performed association testing of common variation in eight regions in 1,318...
18.
Zhang J, Medina-Cleghorn D, Bernal-Mizrachi L, Bracci P, Hubbard A, Conde L, et al.
Oncoscience . 2016 Mar; 3(1):31-41. PMID: 26973858
Diffuse large B-cell lymphoma is an aggressive, genetically heterogenerous disease and the most common type of non-Hodgkin lymphoma among adults. To gain further insights into the etiology of DLBCL and...
19.
Kowalski J, Dwivedi B, Newman S, Switchenko J, Pauly R, Gutman D, et al.
Nucleic Acids Res . 2016 Jan; 44(7):e69. PMID: 26826710
The identification of genes with specific patterns of change (e.g. down-regulated and methylated) as phenotype drivers or samples with similar profiles for a given gene set as drivers of clinical...
20.
Koff J, Ramachandiran S, Bernal-Mizrachi L
Int J Mol Sci . 2015 Jan; 16(2):2942-55. PMID: 25636036
The process of apoptosis is essential for maintaining the physiologic balance between cell death and cell growth. This complex process is executed by two major pathways that participate in activating...