Leo T Chylack Jr
Overview
Explore the profile of Leo T Chylack Jr including associated specialties, affiliations and a list of published articles.
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22
Citations
539
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Recent Articles
11.
Chiu C, Morris M, Rogers G, Jacques P, Chylack Jr L, Tung W, et al.
Am J Clin Nutr
. 2005 Jun;
81(6):1411-6.
PMID: 15941895
Background: Animal studies suggest a role for dietary carbohydrate in cataractogenesis. However, few published human studies have evaluated associations between carbohydrate nutrition and lens opacification. Objective: Our objective was to...
12.
Jacques P, Taylor A, Moeller S, Hankinson S, Rogers G, Tung W, et al.
Arch Ophthalmol
. 2005 Apr;
123(4):517-26.
PMID: 15824226
Objective: To determine if usual nutrient intake is related to a 5-year change in the amount of lens nuclear opacification assessed by computer-assisted image analysis. Design: A sample of 408...
13.
Lu M, Taylor A, Chylack Jr L, Rogers G, Hankinson S, Willett W, et al.
Am J Clin Nutr
. 2005 Apr;
81(4):773-9.
PMID: 15817851
Background: Dietary fat may affect lens cell membrane composition and function, which are related to age-related cataract. Objective: The objective of the study was to examine the association between long-term...
14.
Chylack Jr L, Fu L, Mancini R, Martin-Rehrmann M, Saunders A, Konopka G, et al.
Exp Eye Res
. 2005 Jan;
79(6):941-8.
PMID: 15642333
Lens epithelium-derived growth factor (LEDGF/p75) is a novel transcription co-activator that is critically involved in lens epithelial cell gene regulation and stress responses. Recent evidence indicates that LEDGF/p75 may play...
15.
Fatma N, Kubo E, Chylack Jr L, Shinohara T, Akagi Y, Singh D
Am J Physiol Cell Physiol
. 2004 Jul;
287(2):C508-16.
PMID: 15238362
Retinoic acid (RA) is required for the normal growth and maintenance of many cell types, including lens epithelial cells (LECs). Alcohol (ADH) and aldehyde (ALDH) dehydrogenases are implicated in cellular...
16.
Moeller S, Taylor A, Tucker K, McCullough M, Chylack Jr L, Hankinson S, et al.
J Nutr
. 2004 Jul;
134(7):1812-9.
PMID: 15226474
Few studies have examined the efficacy of the Dietary Guidelines for Americans in the prevention of age-related chronic disease, such as age-related cataract. We examined whether adherence to the Guidelines...
17.
Morris M, Jacques P, Hankinson S, Chylack Jr L, Willett W, Taylor A
Ophthalmic Epidemiol
. 2004 Feb;
11(1):53-65.
PMID: 14977497
Purpose: To study the relationship between alcoholic beverage intake and early lens opacities. Methods: 556 Boston-area women aged 53-74 years were sampled from the Nurses' Health Study cohort. Degree of...
18.
Jacques P, Moeller S, Hankinson S, Chylack Jr L, Rogers G, Tung W, et al.
Am J Clin Nutr
. 2003 Aug;
78(3):400-5.
PMID: 12936921
Background: The association between weight status and the risk of lens opacities has received little attention. Objective: We examined the cross-sectional relations of body mass index (BMI; in kg/m(2)), waist...
19.
Goldstein L, Muffat J, Cherny R, Moir R, Ericsson M, Huang X, et al.
Lancet
. 2003 Apr;
361(9365):1258-65.
PMID: 12699953
Background: Pathological hallmarks of Alzheimer's disease include cerebral beta-amyloid (Abeta) deposition, amyloid accumulation, and neuritic plaque formation. We aimed to investigate the hypothesis that molecular pathological findings associated with Alzheimer's...
20.
Sharma P, Fatma N, Kubo E, Shinohara T, Chylack Jr L, Singh D
J Biol Chem
. 2003 Mar;
278(22):20037-46.
PMID: 12649267
Lens epithelium-cell derived growth factor (LEDGF) is a transcriptional activator. It protects the cells by binding to cis-stress response ((A/T)GGGG(T/A)), and heat shock (HSE; nGAAn) elements in the stress genes...