Lena Alexopoulou
Overview
Explore the profile of Lena Alexopoulou including associated specialties, affiliations and a list of published articles.
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62
Citations
5996
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Recent Articles
1.
Alexopoulou L
Front Immunol
. 2022 Nov;
13:980400.
PMID: 36389822
Sjögren's syndrome (SS) is a chronic systemic autoimmune disease that affects the salivary and lacrimal glands, as well as other organ systems like the lungs, kidneys and nervous system. SS...
2.
Subramanian S, Busch C, Molawi K, Geirsdottir L, Maurizio J, Aguilar S, et al.
Nat Immunol
. 2022 Feb;
23(3):458-468.
PMID: 35210623
Alveolar macrophages (AMs) are lung tissue-resident macrophages that can be expanded in culture, but it is unknown to what extent culture affects their in vivo identity. Here we show that...
3.
Wang Y, Roussel-Queval A, Chasson L, Hanna Kazazian N, Marcadet L, Nezos A, et al.
Front Immunol
. 2021 Jun;
12:676010.
PMID: 34108972
Sjögren's syndrome (SS) is a chronic systemic autoimmune disease that affects predominately salivary and lacrimal glands. SS can occur alone or in combination with another autoimmune disease like systemic lupus...
4.
Hanna Kazazian N, Wang Y, Roussel-Queval A, Marcadet L, Chasson L, Laprie C, et al.
Front Immunol
. 2019 Sep;
10:2015.
PMID: 31552019
Systemic lupus erythematosus (SLE) patients have increased prevalence of metabolic syndrome but the underlying mechanisms are unknown. Toll-like receptor 7 (TLR7) that detects single stranded-RNA plays a key role in...
5.
Choo M, Sano Y, Kim C, Yasuda K, Li X, Lin X, et al.
J Exp Med
. 2017 Apr;
214(5):1297-1311.
PMID: 28400473
The spores of pathogenic bacteria are involved in host entry and the initial encounter with the host immune system. How bacterial spores interact with host immunity, however, remains poorly understood....
6.
Paul A, Acharya D, Le L, Wang P, Stokic D, Leis A, et al.
J Immunol
. 2016 Nov;
197(11):4425-4435.
PMID: 27798161
West Nile virus (WNV) is a neurotropic ssRNA flavivirus that can cause encephalitis, meningitis, and death in humans and mice. Human TLR7 and TLR8 and mouse TLR7 recognize viral ssRNA...
7.
Desnues B, Macedo A, Ordonez-Rueda D, Roussel-Queval A, Malissen B, Bruhns P, et al.
Eur J Immunol
. 2016 Sep;
46(12):2801-2811.
PMID: 27600904
The transcriptional repressor growth factor independence 1 (Gfi1) is important in myeloid and lymphoid differentiation. In the current study we evaluated the involvement of Gfi1 in systemic lupus erythematosus (SLE)....
8.
Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, et al.
PLoS One
. 2015 Mar;
10(3):e0119727.
PMID: 25756897
Innate immune recognition of the major human-specific Gram-positive pathogen Streptococcus pyogenes is not understood. Here we show that mice employ Toll-like receptor (TLR) 2- and TLR13-mediated recognition of S. pyogenes....
9.
Signorino G, Mohammadi N, Patane F, Buscetta M, Venza M, Venza I, et al.
Infect Immun
. 2014 Sep;
82(12):5013-22.
PMID: 25225249
Murine Toll-like receptor 13 (TLR13), an endosomal receptor that is not present in humans, is activated by an unmethylated motif present in the large ribosomal subunit of bacterial RNA (23S...
10.
Salcedo S, Alexopoulou L
Methods Mol Biol
. 2014 Aug;
1197:209-25.
PMID: 25172283
Innate immune recognition of microbial components is critical for the onset of an appropriate immune response against invading pathogens, in particular by dendritic cells. Toll-like receptors (TLRs) are key in...