Leigh Samsel
Overview
Explore the profile of Leigh Samsel including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
36
Citations
1057
Followers
0
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Recent Articles
1.
Pacheco-Rodriguez G, Steagall W, Glasgow C, Onishi R, Stylianou M, Kato J, et al.
Am J Respir Cell Mol Biol
. 2023 May;
68(5):591-594.
PMID: 37125895
No abstract available.
2.
Barbu E, Mendelsohn L, Samsel L, Thein S
Cytokine
. 2019 Nov;
127:154933.
PMID: 31778959
Recurring episodes of acute pain, also referred to as vaso-occlusive crises (VOC), are characteristic of sickle cell disease (SCD), during which pro-inflammatory cytokines, chemokines, adhesion markers and white cell count,...
3.
Pacheco-Rodriguez G, Steagall W, Samsel L, Dagur P, McCoy J, Tunc I, et al.
Chest
. 2019 Apr;
156(2):298-307.
PMID: 31034819
Background: Lymphangioleiomyomatosis (LAM) is a destructive metastasizing neoplasm of the lung characterized by proliferation of LAM cells in specialized lung nodules. LAM cells are characterized by expression of the prometastatic...
4.
Sei Y, Feng J, Samsel L, White A, Zhao X, Yun S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2018 Jun;
315(4):G495-G510.
PMID: 29848020
Lgr5-expressing intestinal stem cells (ISCs) maintain continuous and rapid generation of the intestinal epithelium. Here, we present evidence that dedifferentiation of committed enteroendocrine cells (EECs) contributes to maintenance of the...
5.
Dominical V, Samsel L, McCoy Jr J
Methods
. 2016 Jul;
112:9-17.
PMID: 27461256
Data analysis in imaging flow cytometry incorporates elements of flow cytometry together with other aspects of morphological analysis of images. A crucial early step in this analysis is the creation...
6.
Fertrin K, Samsel L, van Beers E, Mendelsohn L, Kato G, McCoy Jr J
Methods Mol Biol
. 2016 Jul;
1389:279-92.
PMID: 27460253
Hemoglobin S polymerization under hypoxic conditions in sickle cell disorders causes characteristic shape changes to human red blood cells. Previous sickling assays used to investigate the efficacy of novel agents...
7.
Samsel L, McCoy Jr J
Methods Mol Biol
. 2016 Jul;
1389:249-64.
PMID: 27460251
Circulating endothelial cells (CECs) are angiogenic cells that appear in increased numbers in the peripheral circulation either as a result of vascular injury or in response to angiogenic stimuli. Elevated...
8.
Wan C, Andraski A, Spolski R, Li P, Kazemian M, Oh J, et al.
Proc Natl Acad Sci U S A
. 2015 Jul;
112(30):9394-9.
PMID: 26170288
IL-21 is a type I cytokine essential for immune cell differentiation and function. Although IL-21 can activate several STAT family transcription factors, previous studies focused mainly on the role of...
9.
Samsel L, McCoy Jr J
J Immunol Methods
. 2015 Apr;
423:52-9.
PMID: 25858229
Erythroid cell maturation and diseases affecting erythrocytes are frequently accompanied by morphologic and immunophenotypic changes to these cells. In the past, these changes have been assessed primarily through the use...
10.
Cui Y, Onozawa M, Garber H, Samsel L, Wang Z, McCoy J, et al.
Blood
. 2015 Mar;
125(19):2958-67.
PMID: 25814528
T-cell receptors (TCRs) and chimeric antigen receptors recognizing tumor-associated antigens (TAAs) can now be engineered to be expressed on a wide array of immune effectors. Engineered receptors targeting TAAs have...