Lee L Rubin
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Explore the profile of Lee L Rubin including associated specialties, affiliations and a list of published articles.
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100
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7323
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Recent Articles
1.
Cohen O, Sinha M, Wang Y, Daman T, Li P, Deatherage C, et al.
Stroke
. 2025 Feb;
PMID: 39909827
Stroke remains a leading cause of death and disability, underscoring the urgent need for treatments that enhance recovery. Growth Differentiation Factor 11 (GDF11), a member of the TGF-β superfamily, is...
2.
Ximerakis M, Holton K, Giadone R, Ozek C, Saxena M, Santiago S, et al.
Nat Aging
. 2025 Jan;
5(2):333.
PMID: 39881191
No abstract available.
3.
Price F, Matyas M, Gehrke A, Chen W, Wolin E, Holton K, et al.
Nat Biotechnol
. 2024 Sep;
PMID: 39261590
Experimental cell therapies for skeletal muscle conditions have shown little success, primarily because they use committed myogenic progenitors rather than true muscle stem cells, known as satellite cells. Here we...
4.
Leow D, Ng Y, Wang L, Koh H, Zhao T, Khong Z, et al.
J Clin Invest
. 2024 May;
134(12).
PMID: 38722695
Spinal muscular atrophy (SMA) is typically characterized as a motor neuron disease, but extraneuronal phenotypes are present in almost every organ in severely affected patients and animal models. Extraneuronal phenotypes...
5.
Watts M, Giadone R, Ordureau A, Holton K, Harper J, Rubin L
Front Cell Neurosci
. 2024 Feb;
17:1327361.
PMID: 38314348
Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron (MN) disease with severely limited treatment options. Identification of effective treatments has been limited in part by the lack of predictive...
6.
Ben Driss L, Lian J, Walker R, Howard J, Thompson T, Rubin L, et al.
J Cardiovasc Aging
. 2024 Jan;
3(4).
PMID: 38235060
Since the exogenous administration of GDF11, a TGF-ß superfamily member, was reported to have beneficial effects in some models of human disease, there have been many research studies in GDF11...
7.
Berryer M, Tegtmeyer M, Binan L, Valakh V, Nathanson A, Trendafilova D, et al.
iScience
. 2023 Aug;
26(7):106995.
PMID: 37534135
Emerging evidence of species divergent features of astrocytes coupled with the relative inaccessibility of human brain tissue underscore the utility of human pluripotent stem cell (hPSC) technologies for the generation...
8.
Paul K, Krolewski R, Lucumi Moreno E, Blank J, Holton K, Ahfeldt T, et al.
Nat Commun
. 2023 Jun;
14(1):3747.
PMID: 37353544
No abstract available.
9.
Paul K, Krolewski R, Lucumi Moreno E, Blank J, Holton K, Ahfeldt T, et al.
Nat Commun
. 2023 May;
14(1):2803.
PMID: 37193692
Parkinson's disease (PD) is a complex neurodegenerative disease with etiology rooted in genetic vulnerability and environmental factors. Here we combine quantitative epidemiologic study of pesticide exposures and PD with toxicity...
10.
Cronin S, Davidow L, Arvanites A, Rubin L, Penninger J, Woolf C
Bio Protoc
. 2023 May;
13(9):e4666.
PMID: 37188109
Management of neuropathic pain is notoriously difficult; current analgesics, including anti-inflammatory- and opioid-based medications, are generally ineffective and can pose serious side effects. There is a need to uncover non-addictive...