Lee Edsall
Overview
Explore the profile of Lee Edsall including associated specialties, affiliations and a list of published articles.
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11
Citations
4690
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Recent Articles
1.
Shook M, Lu X, Chen X, Parameswaran S, Edsall L, Trimarchi M, et al.
Am J Hum Genet
. 2024 Jan;
111(2):280-294.
PMID: 38183988
Eosinophilic esophagitis (EoE) is a rare atopic disorder associated with esophageal dysfunction, including difficulty swallowing, food impaction, and inflammation, that develops in a small subset of people with food allergies....
2.
Leung D, Jung I, Rajagopal N, Schmitt A, Selvaraj S, Lee A, et al.
Nature
. 2015 Feb;
518(7539):350-354.
PMID: 25693566
Allelic differences between the two homologous chromosomes can affect the propensity of inheritance in humans; however, the extent of such differences in the human genome has yet to be fully...
3.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, et al.
Nature
. 2014 Nov;
515(7527):355-64.
PMID: 25409824
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To...
4.
Cukras C, Gaasterland T, Lee P, Gudiseva H, Chavali V, Pullakhandam R, et al.
PLoS One
. 2012 Nov;
7(11):e50205.
PMID: 23189188
Retinitis Pigmentosa (RP) is a common form of retinal degeneration characterized by photoreceptor degeneration and retinal pigment epithelium (RPE) atrophy causing loss of visual field and acuities. Exome sequencing identified...
5.
Stamatoyannopoulos J, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert D, et al.
Genome Biol
. 2012 Aug;
13(8):418.
PMID: 22889292
To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the same experimental pipelines...
6.
Shen Y, Yue F, McCleary D, Ye Z, Edsall L, Kuan S, et al.
Nature
. 2012 Jul;
488(7409):116-20.
PMID: 22763441
The laboratory mouse is the most widely used mammalian model organism in biomedical research. The 2.6 × 10(9) bases of the mouse genome possess a high degree of conservation with...
7.
Kandarian B, Sethi J, Wu A, Baker M, Yazdani N, Kym E, et al.
Dev Genes Evol
. 2012 Feb;
222(1):29-44.
PMID: 22358128
Gap junctional proteins are important components of signaling pathways required for the development and ongoing functions of all animal tissues, particularly the nervous system, where they function in the intracellular...
8.
Galante P, Parmigiani R, Zhao Q, Caballero O, de Souza J, Navarro F, et al.
Nucleic Acids Res
. 2011 Apr;
39(14):6056-68.
PMID: 21493686
Although patterns of somatic alterations have been reported for tumor genomes, little is known on how they compare with alterations present in non-tumor genomes. A comparison of the two would...
9.
Zhao Q, Kirkness E, Caballero O, Galante P, Parmigiani R, Edsall L, et al.
Genome Biol
. 2010 Nov;
11(11):R114.
PMID: 21108794
Background: To identify potential tumor suppressor genes, genome-wide data from exome and transcriptome sequencing were combined to search for genes with loss of heterozygosity and allele-specific expression. The analysis was...
10.
Macagno E, Gaasterland T, Edsall L, Bafna V, Soares M, Scheetz T, et al.
BMC Genomics
. 2010 Jun;
11:407.
PMID: 20579359
Background: The medicinal leech, Hirudo medicinalis, is an important model system for the study of nervous system structure, function, development, regeneration and repair. It is also a unique species in...