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Raphael B Parmigiani

Explore the profile of Raphael B Parmigiani including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 393
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Recent Articles
1.
Felizardo R, de Almeida D, Pereira R, Watanabe I, Doimo N, Ribeiro W, et al.
FASEB J . 2019 Aug; 33(11):11894-11908. PMID: 31366236
Butyrate is a short-chain fatty acid derived from the metabolism of indigestible carbohydrates by the gut microbiota. Butyrate contributes to gut homeostasis, but it may also control inflammatory responses and...
2.
Jandrey E, Moura R, Andrade L, Machado C, Campesato L, Leite K, et al.
NPJ Breast Cancer . 2019 Apr; 5:11. PMID: 30963110
The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number of positive axillary lymph nodes, complemented with additional clinicopathological factors. However, since lymph...
3.
Pinto S, Sato V, De-Souza E, Ferraz R, Camara H, Pinca A, et al.
Redox Biol . 2018 Jul; 18:84-92. PMID: 29986212
Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging...
4.
Lopes-Ramos C, Barros B, Koyama F, Carpinetti P, Pezuk J, Doimo N, et al.
PLoS One . 2017 Jul; 12(7):e0181153. PMID: 28704519
Background: Genetic studies have largely concentrated on the impact of somatic mutations found in coding regions, and have neglected mutations outside of these. However, 3' untranslated regions (3' UTR) mutations...
5.
Marcola M, Lopes-Ramos C, Pereira E, Cecon E, Fernandes P, Tamura E, et al.
J Cell Physiol . 2016 Jan; 231(9):1953-63. PMID: 26728119
The phenotype of primary cells in culture varies according to the donor environmental condition. We recently showed that the time of the day imposes a molecular program linked to the...
6.
Carpinetti P, Donnard E, Bettoni F, Asprino P, Koyama F, Rozanski A, et al.
Oncotarget . 2015 Oct; 6(35):38360-71. PMID: 26451609
Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the mainstay treatment for locally advanced rectal cancer. Variable degrees of tumor regression are observed after nCRT and alternative treatment strategies, including close...
7.
Lopes-Ramos C, Koyama F, Habr-Gama A, Salim A, Bettoni F, Asprino P, et al.
Cancer Genet . 2015 May; 208(6):319-26. PMID: 25963525
Neoadjuvant chemoradiotherapy (nCRT) may lead to complete tumor regression in rectal cancer patients. Prediction of complete response to nCRT may allow a personalized management of rectal cancer and spare patients...
8.
Hinske L, Galante P, Limbeck E, Mohnle P, Parmigiani R, Ohno-Machado L, et al.
PLoS One . 2015 Mar; 10(3):e0121507. PMID: 25799583
About half of the known miRNA genes are located within protein-coding host genes, and are thus subject to co-transcription. Accumulating data indicate that this coupling may be an intrinsic mechanism...
9.
Donnard E, Carpinetti P, Navarro F, Perez R, Habr-Gama A, Parmigiani R, et al.
Genomics . 2015 Feb; 105(5-6):265-72. PMID: 25666663
Somatically acquired chromosomal rearrangements occur at early stages during tumorigenesis and can be used to indirectly detect tumor cells, serving as highly sensitive and tumor-specific biomarkers. Advances in high-throughput sequencing...
10.
Donnard E, Asprino P, Correa B, Bettoni F, Koyama F, Navarro F, et al.
Oncotarget . 2014 Sep; 5(19):9199-213. PMID: 25193853
We carried out a mutational analysis of 3,594 genes coding for cell surface proteins (Surfaceome) in 23 colorectal cancer cell lines, searching for new altered pathways, druggable mutations and mutated...