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Lee D Larcombe

Explore the profile of Lee D Larcombe including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 67
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Recent Articles
1.
Weber R, Winder C, Larcombe L, Dunn W, Viant M
Metabolomics . 2015 Jun; 11(4):784-786. PMID: 26109924
No abstract available.
2.
Almatrafi A, Feichtinger J, Vernon E, Escobar N, Wakeman J, Larcombe L, et al.
Oncoscience . 2015 Jan; 1(11):745-50. PMID: 25594001
Bona fide germline genes have expression restricted to the germ cells of the gonads. Testis-specific germline development-associated genes can become activated in cancer cells and can potentially drive the oncogenic...
3.
Feichtinger J, McFarlane R, Larcombe L
Database (Oxford) . 2014 Apr; 2014(0):bau024. PMID: 24715218
The identification of cancer-restricted biomarkers is fundamental to the development of novel cancer therapies and diagnostic tools. The construction of comprehensive profiles to define tissue- and cancer-specific gene expression has...
4.
Feichtinger J, McFarlane R, Larcombe L
Database (Oxford) . 2012 Dec; 2012:bas055. PMID: 23241162
The identification of novel candidate markers is a key challenge in the development of cancer therapies. This can be facilitated by putting accessible and automated approaches analysing the current wealth...
5.
Roberts W, Davis F, Holmes J, Collyer S, Larcombe L, Morgan S, et al.
Biosens Bioelectron . 2012 Sep; 41:282-8. PMID: 23017674
The deposition of human RT112 cells in a patterned fashion onto glass substrates and subsequent imaging of the expression of the trans-membrane protein CD44 have been studied using scanning electrochemical...
6.
Stebbeds W, Lunec J, Larcombe L
PLoS One . 2012 Aug; 7(8):e43735. PMID: 22928025
G-quadruplex structures, formed from guanine rich sequences, have previously been shown to be involved in various physiological processes including cancer-related gene expression. Furthermore, G-quadruplexes have been found in several oncogene...
7.
Pankhurst L, Whitby C, Pawlett M, Larcombe L, McKew B, Deacon L, et al.
FEMS Microbiol Ecol . 2011 Oct; 79(1):229-39. PMID: 22029533
In this study, the microbial community within compost, emitted into the airstream, downwind and upwind from a composting facility was characterized and compared through phospholipid fatty acid analysis and 16S...
8.
Piletska E, Stavroulakis G, Larcombe L, Whitcombe M, Sharma A, Primrose S, et al.
Biomacromolecules . 2011 Mar; 12(4):1067-71. PMID: 21361273
Here we present the first molecular imprinted polymer (MIP) that is able to attenuate the biofilm formation of the opportunistic human pathogen Pseudomonas aeruginosa through specific sequestration of its signal...
9.
Fitzgerald T, Larcombe L, Scouarnec S, Clayton S, Rajan D, Carter N, et al.
Bioinformatics . 2011 Mar; 27(9):1195-200. PMID: 21357574
Motivation: The careful normalization of array-based comparative genomic hybridization (aCGH) data is of critical importance for the accurate detection of copy number changes. The difference in labelling affinity between the...