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Leandro C Tabares

Explore the profile of Leandro C Tabares including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 222
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Recent Articles
1.
Tabares L, Daniel D, Vazquez-Ibar J, Kouklovsky C, Alezra V, Un S
J Phys Chem Lett . 2023 Mar; 14(14):3368-3375. PMID: 36995079
Genetic code expansion allows modification of the physical and chemical properties of proteins by the site-directed insertion of noncanonical amino acids. Here we exploit this technology for measuring nanometer-scale distances...
2.
Bonetta R, Hunter G, Trinh C, Borowski T, Fenech A, Kulp M, et al.
Eur Biophys J . 2021 May; 50(3-4):571-585. PMID: 34021366
We have generated a mutant of C. elegans manganese superoxide dismutase at histidine 30 by site-directed mutagenesis. The structure was solved at a resolution of 1.52 Å by X-ray crystallography...
3.
Demay-Drouhard P, Ching H, Decroos C, Guillot R, Li Y, Tabares L, et al.
Phys Chem Chem Phys . 2020 Sep; 22(36):20792-20800. PMID: 32909565
The 285 GHz EPR spectra of perchlorotriphenylmethyl and tetrathiatriarylmethyl radicals in frozen solution have been accurately measured. The relationship between their molecular structures and their g-tensors has been investigated with...
4.
Barwinska-Sendra A, Garcia Y, Sendra K, Basle A, Mackenzie E, Tarrant E, et al.
Nat Commun . 2020 Jun; 11(1):2738. PMID: 32483131
Almost half of all enzymes utilize a metal cofactor. However, the features that dictate the metal utilized by metalloenzymes are poorly understood, limiting our ability to manipulate these enzymes for...
5.
Aslam M, Tabares L, Andreoni A, Canters G, Rutjes F, van Delft F
Pharmaceuticals (Basel) . 2016 Oct; 3(3):679-701. PMID: 27713274
A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization. The dimeric conjugates were evaluated for...
6.
Mascali F, Ching H, Rasia R, Un S, Tabares L
Angew Chem Int Ed Engl . 2016 Aug; 55(37):11041-3. PMID: 27496179
Double electron-electron resonance (DEER) can be used to study the structure of a protein in its native cellular environment. Until now, this has required isolation, in vitro labeling, and reintroduction...
7.
Demay-Drouhard P, Ching H, Akhmetzyanov D, Guillot R, Tabares L, Bertrand H, et al.
Chemphyschem . 2016 Mar; 17(13):2066-78. PMID: 27017296
High-spin gadolinium(III) and manganese(II) complexes have emerged as alternatives to standard nitroxide radical spin labels for measuring nanometric distances by using pulsed electron-electron double resonance (PELDOR or DEER) at high...
8.
Ching H, Mascali F, Bertrand H, Bruch E, Demay-Drouhard P, Rasia R, et al.
J Phys Chem Lett . 2016 Mar; 7(6):1072-6. PMID: 26938795
A genetically encodable paramagnetic spin-label capable of self-assembly from naturally available components would offer a means for studying the in-cell structure and interactions of a protein by electron paramagnetic resonance...
9.
Ching H, Demay-Drouhard P, Bertrand H, Policar C, Tabares L, Un S
Phys Chem Chem Phys . 2015 Aug; 17(36):23368-77. PMID: 26287752
Pulse electron-electron double resonance (PELDOR) is a versatile technique for probing the structures and functions of complex biological systems. Despite the recent interest in high-spin metal-ions for high field/frequency applications,...
10.
Bruch E, Warner M, Thomine S, Tabares L, Un S
J Phys Chem B . 2015 Mar; 119(43):13515-23. PMID: 25730710
The ability to characterize the structure of metal centers beyond their primary ligands is important to understanding their chemistry. High-magnetic-field pulsed electron double resonance detected NMR (ELDOR-NMR) is shown to...