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Helene C Bertrand

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Articles 19
Citations 241
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Recent Articles
1.
Neumann T, Ramu V, Bertin J, He M, Vervisch C, Coogan M, et al.
Inorg Chem . 2024 Jan; 63(2):1197-1213. PMID: 38164793
We describe the preparation, characterization, and imaging studies of rhenium carbonyl complexes with a pyta (4-(2-pyridyl)-1,2,3-triazole) or tapy (1-(2-pyridyl)-1,2,3-triazole)-based heteroaromatic N∧N ligand and thiolate or selenoate X ligand. The stability...
2.
Prieux-Klotz C, Chedotal H, Zoumpoulaki M, Chouzenoux S, Chene C, Lopez-Sanchez A, et al.
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36361753
Reactive oxygen species (ROS) are produced by every aerobic cell during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. Superoxide Dismutases (SOD) are...
3.
Nagarajan S, Poyer F, Fourmois L, Naud-Martin D, Medjoubi K, Somogyi A, et al.
Chemistry . 2022 Jan; 28(15):e202104424. PMID: 35076130
Triphenylamine (TP) derivatives such as two-branch cationic vinylbenzimidazolium triphenylamine TP-2Bzim are promising turn-on fluorescent probes suitable for two-photon imaging, labelling mitochondria in live cells. Here, we designed two TP-2Bzim derivatives...
4.
Policar C, Bouvet J, Bertrand H, Delsuc N
Curr Opin Chem Biol . 2022 Jan; 67:102109. PMID: 35066373
Superoxide dismutases (SODs) are metalloproteins that protect cells against oxidative stress by controlling the concentration of superoxide (O) through catalysis of its dismutation. The activity of superoxide dismutases can be...
5.
Demay-Drouhard P, Ching H, Decroos C, Guillot R, Li Y, Tabares L, et al.
Phys Chem Chem Phys . 2020 Sep; 22(36):20792-20800. PMID: 32909565
The 285 GHz EPR spectra of perchlorotriphenylmethyl and tetrathiatriarylmethyl radicals in frozen solution have been accurately measured. The relationship between their molecular structures and their g-tensors has been investigated with...
6.
Mathieu E, Bernard A, Ching H, Somogyi A, Medjoubi K, Fores J, et al.
Dalton Trans . 2020 Feb; 49(7):2323-2330. PMID: 32022053
A superoxide dismutase mimic (Mn1) was functionalized with three positively charged-peptides: RRRRRRRRR (Mn1-R9), RRWWWRRWRR (Mn1-RW9) or F-r-F-K (Mn1-MPP). Characterization of the physico-chemical properties of the complexes show that they share...
7.
Guillaumot M, Cerles O, Bertrand H, Benoit E, Nicco C, Chouzenoux S, et al.
Oncotarget . 2019 Nov; 10(60):6418-6431. PMID: 31741707
By using the differential in level of oxidative status between normal and cancer cells, SuperOxide Dismutase (SOD) mimetics can have anti-tumor efficacy and prevent oxaliplatin-induced peripheral neuropathy. Our objective was...
8.
Dilly S, Fotso Fotso A, Lejal N, Zedda G, Chebbo M, Rahman F, et al.
J Med Chem . 2018 Jul; 61(16):7202-7217. PMID: 30028133
The nucleoprotein (NP) of influenza A virus (IAV) required for IAV replication is a promising target for new antivirals. We previously identified by in silico screening naproxen being a dual...
9.
Henry L, Delsuc N, Laugel C, Lambert F, Sandt C, Hostachy S, et al.
Bioconjug Chem . 2018 Jan; 29(4):987-991. PMID: 29360339
Hyaluronic acids were labeled with a rhenium-tricarbonyl used as single core multimodal probe for imaging and their penetration into human skin biopsies was studied using IR microscopy and fluorescence imaging...
10.
Kerr F, Sofola-Adesakin O, Ivanov D, Gatliff J, Perez-Nievas B, Bertrand H, et al.
PLoS Genet . 2017 Mar; 13(3):e1006593. PMID: 28253260
Nrf2, a transcriptional activator of cell protection genes, is an attractive therapeutic target for the prevention of neurodegenerative diseases, including Alzheimer's disease (AD). Current Nrf2 activators, however, may exert toxicity...