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Leah M Hunter

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Recent Articles
1.
Hunter L, Kite J, Fletcher-Etherington A, Nightingale K, Nobre L, Antrobus R, et al.
J Gen Virol . 2024 Apr; 105(4). PMID: 38687323
The human cytomegalovirus (HCMV) pUS2 glycoprotein exploits the host's endoplasmic reticulum (ER)-associated degradation (ERAD) pathway to degrade major histocompatibility complex class I (MHC-I) and prevent antigen presentation. Beyond MHC-I, pUS2...
2.
Li H, Fletcher-Etherington A, Hunter L, Keshri S, Fielding C, Nightingale K, et al.
Cell Host Microbe . 2024 Mar; 32(4):466-478.e11. PMID: 38479395
Human cytomegalovirus (HCMV) is an important human pathogen that regulates host immunity and hijacks host compartments, including lysosomes, to assemble virions. We combined a quantitative proteomic analysis of HCMV infection...
3.
Nightingale K, Potts M, Hunter L, Fielding C, Zerbe C, Fletcher-Etherington A, et al.
Proc Natl Acad Sci U S A . 2022 Feb; 119(6). PMID: 35105802
Human cytomegalovirus (HCMV) is an important human pathogen and a paradigm of viral immune evasion, targeting intrinsic, innate, and adaptive immunity. We have employed two orthogonal multiplexed tandem mass tag-based...
4.
Soday L, Potts M, Hunter L, Ravenhill B, Houghton J, Williamson J, et al.
Front Immunol . 2021 Feb; 12:600056. PMID: 33628210
The cellular response to interferon (IFN) is essential for antiviral immunity, IFN-based therapy and IFN-related disease. The plasma membrane (PM) provides a critical interface between the cell and its environment,...
5.
Soh T, Davies C, Muenzner J, Hunter L, Barrow H, Connor V, et al.
Cell Rep . 2020 Oct; 33(1):108235. PMID: 33027661
Herpesviruses are ubiquitous in the human population and they extensively remodel the cellular environment during infection. Multiplexed quantitative proteomic analysis over the time course of herpes simplex virus 1 (HSV-1)...