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Layla Thurston

Explore the profile of Layla Thurston including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 349
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Recent Articles
1.
Mills E, Thurston L, Yang L, Hunjan T, Phylactou M, Patel B, et al.
J Clin Endocrinol Metab . 2025 Mar; PMID: 40036336
Background: Kisspeptin is a critical endogenous activator of the reproductive system, with escalating clinical interest as a novel therapeutic for common reproductive and psychosexual disorders. However, conflicting animal data suggest...
2.
Ertl N, Mills E, Wall M, Thurston L, Yang L, Suladze S, et al.
Sci Rep . 2024 May; 14(1):11051. PMID: 38745001
Distressing low sexual desire, termed Hypoactive Sexual Desire Disorder (HSDD), affects approximately 10% of women and 8% of men. In women, the 'top-down' theory of HSDD describes hyperactivity in higher-level...
3.
Abbara A, Adams S, Phylactou M, Izzi-Engbeaya C, Mills E, Thurston L, et al.
Fertil Steril . 2023 Nov; 121(2):334-345. PMID: 37977226
Objective: To quantify how representative a single measure of reproductive hormone level is of the daily hormonal profile using data from detailed hormonal sampling in the saline placebo-treated arm conducted...
4.
Mills E, Ertl N, Wall M, Thurston L, Yang L, Suladze S, et al.
JAMA Netw Open . 2023 Feb; 6(2):e2254313. PMID: 36735255
Importance: The human physiological sexual response is crucial for reward, satisfaction, and reproduction. Disruption of the associated neurophysiological pathways predisposes to low sexual desire; the most prevalent psychological form is...
5.
Thurston L, Hunjan T, Ertl N, Wall M, Mills E, Suladze S, et al.
JAMA Netw Open . 2022 Oct; 5(10):e2236131. PMID: 36287566
Importance: Despite being the most common female sexual health complaint worldwide, current treatment options for hypoactive sexual desire disorder (HSDD) are limited in their safety and effectiveness. The hormone kisspeptin...
6.
Thurston L, Hunjan T, Mills E, Wall M, Ertl N, Phylactou M, et al.
J Clin Invest . 2022 Oct; 132(19). PMID: 36189794
BACKGROUNDHypoactive sexual desire disorder (HSDD) is characterized by a persistent deficiency of sexual fantasies and desire for sexual activity, causing marked distress and interpersonal difficulty. It is the most prevalent...
7.
Comninos A, Yang L, OCallaghan J, Mills E, Wall M, Demetriou L, et al.
Psychoneuroendocrinology . 2021 May; 129:105244. PMID: 33975151
Gamma-aminobutyric acid (GABA) is a key inhibitory neurotransmitter that has been implicated in the aetiology of common mood and behavioural disorders. By employing proton magnetic resonance spectroscopy in man, we...
8.
Khoo B, Tan T, Clarke S, Mills E, Patel B, Modi M, et al.
J Clin Endocrinol Metab . 2020 Nov; 106(2):e803-e811. PMID: 33180932
Context: The effects of COVID-19 on the thyroid axis remain uncertain. Recent evidence has been conflicting, with both thyrotoxicosis and suppression of thyroid function reported. Objective: We aimed to detail...
9.
Yang L, Demetriou L, Wall M, Mills E, Wing V, Thurston L, et al.
J Clin Endocrinol Metab . 2020 Oct; 106(4):e1837-e1848. PMID: 33075807
Context: The hormone kisspeptin has crucial and well-characterized roles in reproduction. Emerging data from animal models also suggest that kisspeptin has important metabolic effects including modulation of food intake. However,...
10.
Tan T, Khoo B, Mills E, Phylactou M, Patel B, Eng P, et al.
Lancet Diabetes Endocrinol . 2020 Sep; 8(10):809-810. PMID: 32946818
No abstract available.