Ali Abbara
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Explore the profile of Ali Abbara including associated specialties, affiliations and a list of published articles.
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104
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1373
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Recent Articles
1.
Mills E, Thurston L, Yang L, Hunjan T, Phylactou M, Patel B, et al.
J Clin Endocrinol Metab
. 2025 Mar;
PMID: 40036336
Background: Kisspeptin is a critical endogenous activator of the reproductive system, with escalating clinical interest as a novel therapeutic for common reproductive and psychosexual disorders. However, conflicting animal data suggest...
2.
Pierret A, Patel A, Daniels E, Comninos A, Dhillo W, Abbara A
Andrology
. 2025 Jan;
PMID: 39834030
The hypothalamic-pituitary-gonadal axis is regulated by the gonadotropin-releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release...
3.
Koysombat K, Tsoutsouki J, Patel A, Comninos A, Dhillo W, Abbara A
Physiol Rev
. 2025 Jan;
105(2):707-764.
PMID: 39813600
Kisspeptin and neurokinin B (NKB) play a key role in several physiological processes including in puberty, adult reproductive function including the menstrual cycle, as well as mediating the symptoms of...
4.
Hanassab S, Nelson S, Akbarov A, Yeung A, Hramyka A, Alhamwi T, et al.
Nat Commun
. 2025 Jan;
16(1):296.
PMID: 39779682
Infertility affects one-in-six couples, often necessitating in vitro fertilization treatment (IVF). IVF generates complex data, which can challenge the utilization of the full richness of data during decision-making, leading to...
5.
Gak N, Abbara A, Dhillo W, Keen R, Comninos A
Front Endocrinol (Lausanne)
. 2024 Dec;
15:1494965.
PMID: 39703866
Normal pregnancy and lactation have a marked physiological impact on maternal bone metabolism. This impact is usually temporary and reversible, but some women sustain fragility fractures whilst pregnant or lactating,...
6.
Campos F, Sharma A, Patel B, Papadopoulou D, Comninos A, Abbara A
J Clin Med
. 2024 Nov;
13(22).
PMID: 39598112
Liver dysfunction can occur in patients presenting with thyrotoxicosis, due to several different aetiologies. A 42-year-old man had mild liver dysfunction on presentation with hyperthyroidism due to Graves' disease (GD):...
7.
Patel A, Koysombat K, Pierret A, Young M, Comninos A, Dhillo W, et al.
Ann N Y Acad Sci
. 2024 Sep;
1540(1):21-46.
PMID: 39287750
Functional hypothalamic amenorrhea (FHA) is one of the most common causes of secondary amenorrhea, resulting in anovulation and infertility, and is a low estrogen state that increases the risk of...
8.
Mills E, Abbara A, Dhillo W, Comninos A
Ann N Y Acad Sci
. 2024 Sep;
1540(1):47-60.
PMID: 39269749
The neuropeptide kisspeptin and its cognate receptor have been extensively studied in reproductive physiology, with diverse and well-established functions, including as an upstream regulator of pubertal onset, reproductive hormone secretion,...
9.
Walford H, Tyler B, Abbara A, Clarke S, Talaulikar V, Wattar B
Clin Endocrinol (Oxf)
. 2024 Aug;
101(5):535-548.
PMID: 39155620
Introduction: Polycystic ovarian syndrome (PCOS) is the commonest endocrine condition affecting reproductive age women. Many biomarkers may aid assessment and management, however evidence is limited on their utility in clinical...
10.
Abbara A, Dhillo W
J Clin Invest
. 2024 Aug;
134(15).
PMID: 39087475
Kisspeptin is an essential neuropeptide sitting at the apex of the hypothalamo-pituitary-gonadal (HPG) endocrine axis to regulate gonadotropin-releasing hormone (GnRH) neurons and downstream reproductive hormones. Kisspeptin neurons integrate feedback from...