Lawrence T C Ong
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Explore the profile of Lawrence T C Ong including associated specialties, affiliations and a list of published articles.
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7
Citations
39
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Recent Articles
1.
Afrasiabi A, Keane J, Ong L, Alinejad-Rokny H, Fewings N, Booth D, et al.
J Autoimmun
. 2021 Dec;
127:102781.
PMID: 34952359
To investigate the molecular mechanisms through which Epstein-Barr virus (EBV) may contribute to Systemic Lupus Erythematosus (SLE) pathogenesis, we interrogated SLE genetic risk loci for signatures of EBV infection. We...
2.
Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk
Ong L, Schibeci S, Fewings N, Booth D, Parnell G
Epigenetics Chromatin
. 2021 Feb;
14(1):9.
PMID: 33541415
Background: The mechanisms linking UV radiation and vitamin D exposure to the risk of acquiring the latitude and critical period-dependent autoimmune disease, multiple sclerosis, is unclear. We examined the effect...
3.
Ong L, Booth D, Parnell G
Mol Nutr Food Res
. 2020 Oct;
64(23):e2000437.
PMID: 33079481
DNA methylation is increasingly being recognized as a mechanism through which environmental exposures confer disease risk. Several studies have examined the association between vitamin D and changes in DNA methylation...
4.
Ong L, Parnell G, Veale K, Stewart G, Liddle C, Booth D
Genes Immun
. 2020 Oct;
21(5):335-347.
PMID: 33037402
Multiple lines of evidence indicate Multiple Sclerosis (MS) is affected by vitamin D. This effect may be mediated by methylation in immune cell progenitors. We aimed to determine (1) if...
5.
Ong L, Parnell G, Afrasiabi A, Stewart G, Swaminathan S, Booth D
Genes Immun
. 2019 Oct;
21(2):91-99.
PMID: 31619767
Epstein-Barr Virus (EBV) infection appears to be necessary for the development of Multiple Sclerosis (MS), although the specific mechanisms are unknown. More than 200 single-nucleotide polymorphisms (SNPs) are known to...
6.
Ong L, Galambos G, Brown D
Front Psychiatry
. 2017 Jul;
8:124.
PMID: 28744230
There is an increasing awareness that autoimmune diseases can present with neuropsychiatric manifestations. We present the case of a 17-year-old female requiring psychiatric hospitalization for obsessive-compulsive disorder and major depressive...
7.
Mak J, Kim L, Ong L, Bui T
Med J Aust
. 2010 Jun;
192(12):719-20.
PMID: 20565354
A 90-year-old man presented to the emergency department with multiple symptoms including double vision, reduced mobility, dysphagia, recent rapid weight loss, ear discharge and deafness. He had diabetes and other...