Lauryn Choleva
Overview
Explore the profile of Lauryn Choleva including associated specialties, affiliations and a list of published articles.
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7
Citations
50
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0
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Recent Articles
1.
Wang P, Wood O, Choleva L, Liu H, Karakose E, Lambertini L, et al.
bioRxiv
. 2024 May;
PMID: 38798411
The small molecule DYRK1A inhibitor, harmine, induces human beta cell proliferation, expands beta cell mass, enhances expression of beta cell phenotypic genes, and improves human beta cell function i and...
2.
Wu V, Choleva L, Wilkes M
Endocrinol Metab Clin North Am
. 2024 Jan;
53(1):27-38.
PMID: 38272596
Changes in physical growth, neurocognitive development, and pubertal maturation are some of the challenges to achieving blood glucose targets in children with type 1 diabetes mellitus. To optimize glycemic outcomes,...
3.
Choleva L, Wang P, Liu H, Wood O, Lambertini L, Scott D, et al.
Endocrinology
. 2023 Dec;
165(2).
PMID: 38151968
Mutations in CDKN1C, encoding p57KIP2, a canonical cell cycle inhibitor, underlie multiple pediatric endocrine syndromes. Despite this central role in disease, little is known about the structure and function of...
4.
Choleva L, Wilkes M
JCEM Case Rep
. 2023 Nov;
1(6):luad131.
PMID: 37946725
β-Thalassemia is characterized by the abnormal synthesis of β-hemoglobin chains resulting in hemolytic anemia. Treatment involves frequent blood transfusions, which leads to deposition of iron in many organs, including endocrine...
5.
Wang P, Karakose E, Argmann C, Wang H, Balev M, Brody R, et al.
J Clin Invest
. 2022 Jun;
132(15).
PMID: 35700053
Resistance to regeneration of insulin-producing pancreatic β cells is a fundamental challenge for type 1 and type 2 diabetes. Recently, small molecule inhibitors of the kinase DYRK1A have proven effective...
6.
Wang P, Karakose E, Choleva L, Kumar K, DeVita R, Garcia-Ocana A, et al.
Front Endocrinol (Lausanne)
. 2021 Aug;
12:671946.
PMID: 34335466
A quantitative deficiency of normally functioning insulin-producing pancreatic beta cells is a major contributor to all common forms of diabetes. This is the underlying premise for attempts to replace beta...
7.
Dubnov-Raz G, Rinat B, Hemila H, Choleva L, Cohen A, Constantini N
Pediatr Exerc Sci
. 2014 Jul;
27(1):113-9.
PMID: 25050610
Observational studies identified associations between vitamin D insufficiency (serum 25(OH)D < 30ng·ml-1) and risk of upper respiratory infection (URI). Swimmers are highly prone to URIs, which might hinder their performance....