Lauri J Sipila
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Explore the profile of Lauri J Sipila including associated specialties, affiliations and a list of published articles.
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10
Citations
40
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0
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Recent Articles
1.
Sipila L, Tanskanen T, Heikkinen S, Seppa K, Aavikko M, Ravantti J, et al.
Acta Oncol
. 2024 Nov;
63:841-849.
PMID: 39492803
Background And Purpose: Many non-neoplastic diseases have been established to be tumorigenic, and cancers are sometimes misdiagnosed as non-neoplastic diseases. We conducted a comprehensive registry-based study of site-specific cancer diagnosis...
2.
Sipila L, Aavikko M, Ravantti J, Martin S, Kuopio T, Lahtinen L, et al.
Fam Cancer
. 2024 Jun;
23(4):647-652.
PMID: 38847920
Some 50% of Finnish Lynch Syndrome (LS) cases are caused by a founder variant in MLH1, in which the entire exon 16 has been lost due to an Alu-mediated recombination...
3.
Sipila L, Katainen R, Aavikko M, Ravantti J, Donner I, Lehtonen R, et al.
Genes Environ
. 2024 May;
46(1):12.
PMID: 38711096
Background: Sinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the non-intestinal-type sinonasal adenocarcinoma (non-ITAC). Occurrence of ITAC is strongly associated with exposure...
4.
Sipila L, Seppa K, Aavikko M, Ravantti J, Heikkinen S, Aaltonen L, et al.
Sci Rep
. 2022 Sep;
12(1):15126.
PMID: 36068325
Despite the fact that the effect of sex on the occurrence of cancers has been studied extensively, it remains unclear whether sex modifies familial aggregation of cancers. We explored sex-specific...
5.
Kuisma H, Bramante S, Rajamaki K, Sipila L, Kaasinen E, Kaukomaa J, et al.
Nat Commun
. 2021 Sep;
12(1):5448.
PMID: 34521855
Mechanical forces in a constrained cellular environment were recently established as a facilitator of chromosomal damage. Whether this could contribute to tumorigenesis is not known. Uterine leiomyomas are common neoplasms...
6.
Donner I, Sipila L, Plaketti R, Kuosmanen A, Forsstrom L, Katainen R, et al.
Vascular
. 2021 Jul;
30(5):842-847.
PMID: 34281442
Background: Visceral artery aneurysms (VAAs) can be fatal if ruptured. Although a relatively rare incident, it holds a contemporary mortality rate of approximately 12%. VAAs have multiple possible causes, one...
7.
Aavikko M, Kaasinen E, Andersson N, Pentinmikko N, Sulo P, Donner I, et al.
Hum Mol Genet
. 2021 Jul;
30(24):2429-2440.
PMID: 34274970
Many hereditary cancer syndromes are associated with an increased risk of small and large intestinal adenocarcinomas. However, conditions bearing a high risk to both adenocarcinomas and neuroendocrine tumors are yet...
8.
Rinne S, Sipila L, Sulo P, Jouanguy E, Beziat V, Abel L, et al.
Open Forum Infect Dis
. 2019 Oct;
6(10):ofz337.
PMID: 31660331
Familial clustering of classic Kaposi sarcoma (CKS) is rare with, approximately 100 families reported to date. We studied 2 consanguineous families, 1 Iranian and 1 Israeli, with multiple cases of...
9.
Donner I, Katainen R, Kaasinen E, Aavikko M, Sipila L, Pukkala E, et al.
Fam Cancer
. 2018 Aug;
18(1):113-119.
PMID: 30097855
Angioimmunoblastic T-cell lymphoma (AITL) is a subtype of peripheral T-cell lymphoma with a poor prognosis: the 5-year survival rate is approximately 30%. Somatic driver mutations have been found in TET2,...
10.
Donner I, Katainen R, Sipila L, Aavikko M, Pukkala E, Aaltonen L
Lung Cancer
. 2018 Jul;
122:76-82.
PMID: 30032850
Objectives: Although the primary cause of lung cancer is smoking, a considerable proportion of all lung cancers occur in never smokers. Gender influences the risk and characteristics of lung cancer...