Laurence H Beck
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Explore the profile of Laurence H Beck including associated specialties, affiliations and a list of published articles.
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7
Citations
206
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Recent Articles
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Haddad G, Lorenzen J, Ma H, de Haan N, Seeger H, Zaghrini C, et al.
J Clin Invest
. 2020 Dec;
131(5).
PMID: 33351779
Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome in adults. In most cases, this autoimmune kidney disease is associated with autoantibodies against the M-type phospholipase A2 receptor...
3.
Larsen C, Cossey L, Beck L
Mod Pathol
. 2016 Feb;
29(4):421-6.
PMID: 26847174
Thrombospondin type I domain-containing 7A (THSD7A) is a known antigenic target of autoantibodies leading to primary membranous glomerulopathy and was reported to account for ~10% of phospholipase A2 receptor (PLA2R)-negative...
4.
Beck L
Kidney Int
. 2015 Feb;
87(3):494-7.
PMID: 25723631
Fetomaternal alloimmunization against neutral endopeptidase (NEP) is a rare cause of antenatal membranous nephropathy, yet lessons from such cases continue to elucidate important pathophysiologic points. Vivarelli and colleagues describe two...
5.
Hladunewich M, Cattran D, Beck L, Odutayo A, Sethi S, Ayalon R, et al.
Nephrol Dial Transplant
. 2014 Apr;
29(8):1570-7.
PMID: 24714414
Background: H.P. Acthar(®) Gel is currently the only Food and Drug Administration therapy approved for the treatment of nephrotic syndrome. Active drug ingredients include structurally related melanocortin peptides that bind...
6.
Irazabal M, Eirin A, Lieske J, Beck L, Sethi S, Borland T, et al.
Nephrol Dial Transplant
. 2012 Sep;
28(1):137-46.
PMID: 22987142
Background: Selective urinary biomarkers have been considered superior to total proteinuria in predicting response to treatment and outcome in patients with membranous nephropathy (MN). Methods: We prospectively tested whether urinary...
7.
Bonegio R, Beck L, Kahlon R, Lu W, Salant D
Kidney Int
. 2011 Jan;
79(10):1099-112.
PMID: 21270765
To determine which nephron segments require Notch signals for development, we conditionally deleted Rbpj, a transcription factor required for canonical Notch signaling, in nephrogenic progenitors (NPs) of the metanephric mesenchyme....