Lauren D Black 3rd
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Explore the profile of Lauren D Black 3rd including associated specialties, affiliations and a list of published articles.
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30
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656
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Recent Articles
1.
Perreault L, Daley M, Watson M, Rastogi S, Jaiganesh A, Porter E, et al.
Front Cell Dev Biol
. 2024 Mar;
12:1279932.
PMID: 38434619
Heart failure afflicts an estimated 6.5 million people in the United States, driven largely by incidents of coronary heart disease (CHD). CHD leads to heart failure due to the inability...
2.
Watson M, Williams C, Wang R, Perreault L, Sullivan K, Stoppel W, et al.
Front Cardiovasc Med
. 2022 Dec;
9:993310.
PMID: 36518682
Introduction: Birth defects, particularly those that affect development of the heart, are a leading cause of morbidity and mortality in infants and young children. Babies born with heart hypoplasia (heart...
3.
Shaughnessey E, Kann S, Azizgolshani H, Black 3rd L, Charest J, Vedula E
Sci Rep
. 2022 Aug;
12(1):13182.
PMID: 35915212
Rapid non-invasive kidney-specific readouts are essential to maximizing the potential of microfluidic tissue culture platforms for drug-induced nephrotoxicity screening. Transepithelial electrical resistance (TEER) is a well-established technique, but it has...
4.
Porter E, Stoppel W, Kudej R, Black 3rd L
Methods Mol Biol
. 2022 May;
2485:299-309.
PMID: 35618914
Tetralogy of Fallot (ToF) is a severe congenital heart defect (CHD) that requires surgical reconstruction soon after birth. Reconstructive surgery involves the implantation of synthetic cardiovascular patches to widen the...
5.
Huang M, Smith A, Watson M, Bhandari R, Baugh L, Ivanovska I, et al.
Arthritis Rheumatol
. 2022 Feb;
74(7):1245-1256.
PMID: 35212485
Objective: The development of precision therapeutics for systemic sclerosis (SSc) has been hindered by the lack of models that accurately mimic the disease in vitro. This study was undertaken to...
6.
Perreault L, Le T, Oudin M, Black 3rd L
Physiol Genomics
. 2021 Jul;
53(10):414-429.
PMID: 34281425
Cardiac fibroblasts are responsible for extracellular matrix turnover and repair in the cardiac environment and serve to help facilitate immune responses. However, it is well established that they have a...
7.
Daley M, Bonzanni M, MacKenzie A, Kaplan D, Black 3rd L
Biochem Biophys Res Commun
. 2020 Aug;
530(1):240-245.
PMID: 32828293
Historically, the field of tissue engineering has been adept at modulating the chemical and physical microenvironment. This approach has yielded significant progress, but it is imperative to further integrate our...
8.
Wang Y, Huang W, Wang Y, Mu X, Ling S, Yu H, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(25):14602-14608.
PMID: 32522869
Bioinspired actuators with stimuli-responsive and deformable properties are being pursued in fields such as artificial tissues, medical devices and diagnostics, and intelligent biosensors. These applications require that actuator systems have...
9.
Sood D, Cairns D, Dabbi J, Ramakrishnan C, Deisseroth K, Black 3rd L, et al.
Sci Rep
. 2019 Dec;
9(1):17874.
PMID: 31784595
Brain extracellular matrix (ECM) is often overlooked in vitro brain tissue models, despite its instructive roles during development. Using developmental stage-sourced brain ECM in reproducible 3D bioengineered culture systems, we...
10.
Sood D, Tang-Schomer M, Pouli D, Mizzoni C, Raia N, Tai A, et al.
Nat Commun
. 2019 Oct;
10(1):4529.
PMID: 31586101
Dynamic alterations in the unique brain extracellular matrix (ECM) are involved in malignant brain tumors. Yet studies of brain ECM roles in tumor cell behavior have been difficult due to...