Laura V Ashton
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Explore the profile of Laura V Ashton including associated specialties, affiliations and a list of published articles.
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17
Citations
237
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Recent Articles
1.
Ashton L, Weishaar K, Seguin B, MacNeill A
Biomedicines
. 2023 Sep;
11(9).
PMID: 37760788
Human rhabdomyosarcomas are rarely cured by surgical resection alone. This is also true for high-grade soft tissue sarcomas in dogs. Dogs with spontaneous sarcoma are good models for clinical responses...
2.
Saklou N, Burgess B, Ashton L, Morley P, Goehring L
Equine Vet J
. 2020 Jun;
53(2):349-355.
PMID: 32557765
Background: Equid herpesvirus type 1 (EHV-1) is ubiquitous in equine populations causing respiratory disease, and complications including late-term abortion and neurological disease. Eradication of EHV-1 from housing environments that typically...
3.
Ashton L, Graham B, Afzali M, Gustafson D, MacNeill A
Oncolytic Virother
. 2020 Jun;
9:17-29.
PMID: 32548076
Purpose: Rhabdomyosarcomas (RMS) are difficult tumors to treat with conventional therapies. Publications indicate that oncolytic virotherapy (OV) could benefit cancer patients with tumors that are refractory to conventional treatments. It...
4.
Ashton L, Quackenbush S, Castle J, Wilson G, McCoy J, Jordan M, et al.
Viruses
. 2020 May;
12(5).
PMID: 32397134
The poxvirus, myxoma virus (MYXV) has shown efficacy as an oncolytic virus (OV) in some cancer models. However, MYXV replication within murine cancer models and spontaneous canine sarcomas is short-lived....
5.
Fitzgerald B, Molins C, Islam M, Graham B, Hove P, Wormser G, et al.
J Proteome Res
. 2019 Dec;
19(2):610-623.
PMID: 31821002
Lyme disease is a tick-borne bacterial illness that occurs in areas of North America, Europe, and Asia. Early infection typically presents as generalized symptoms with an erythema migrans (EM) skin...
6.
Pegalajar-Jurado A, Fitzgerald B, Islam M, Belisle J, Wormser G, Waller K, et al.
Sci Rep
. 2018 Aug;
8(1):12204.
PMID: 30111850
Metabolites detectible in human biofluids are attractive biomarkers for the diagnosis of early Lyme disease (ELD), a vector-borne infectious disease. Urine represents an easily obtained clinical sample that can be...
7.
Pegalajar-Jurado A, Schriefer M, Welch R, Couturier M, Mackenzie T, Clark R, et al.
J Clin Microbiol
. 2018 May;
56(8).
PMID: 29743307
Standard two-tiered testing (STTT) is the recommended algorithm for laboratory diagnosis of Lyme disease (LD). Several limitations are associated with STTT that include low sensitivity in the early stages of...
8.
Molins C, Ashton L, Wormser G, Andre B, Hess A, Delorey M, et al.
Sci Transl Med
. 2017 Aug;
9(403).
PMID: 28814545
Lyme disease, the most commonly reported vector-borne disease in the United States, results from infection with Early clinical diagnosis of this disease is largely based on the presence of an...
9.
Molins C, Ashton L, Wormser G, Hess A, Delorey M, Mahapatra S, et al.
Clin Infect Dis
. 2015 Mar;
60(12):1767-75.
PMID: 25761869
Background: Early Lyme disease patients often present to the clinic prior to developing a detectable antibody response to Borrelia burgdorferi, the etiologic agent. Thus, existing 2-tier serology-based assays yield low...
10.
Molins C, Sexton C, Young J, Ashton L, Pappert R, Beard C, et al.
J Clin Microbiol
. 2014 Aug;
52(10):3755-62.
PMID: 25122862
Serological assays and a two-tiered test algorithm are recommended for laboratory confirmation of Lyme disease. In the United States, the sensitivity of two-tiered testing using commercially available serology-based assays is...