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Laura Tsujikawa

Explore the profile of Laura Tsujikawa including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 133
Followers 0
Related Specialties
Biochemistry
Science
General Medicine
Top 10 Co-Authors
Pieter L deHaseth
Norman C W Wong
Michael G Strainic
Andre White
Sylwia Wasiak
Henrik C Hansen
Olesya A Kharenko
Mary D Barkley
Sarah Attwell
Peter R Young
Published In
Proc Natl Acad Sci U S A
Methods Enzymol
Biochemistry
J Bacteriol
Nucleic Acids Res
Affiliations
Soon will be listed here.
Recent Articles
1.
RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist
McLure K, Gesner E, Tsujikawa L, Kharenko O, Attwell S, Campeau E, et al.
PLoS One . 2014 Jan; 8(12):e83190. PMID: 24391744
Increased synthesis of Apolipoprotein A-I (ApoA-I) and HDL is believed to provide a new approach to treating atherosclerosis through the stimulation of reverse cholesterol transport. RVX-208 increases the production of...
2.
Mutational analysis of Escherichia coli heat shock transcription factor sigma 32 reveals similarities with sigma 70 in recognition of the -35 promoter element and differences in promoter DNA melting and -10 recognition
Kourennaia O, Tsujikawa L, deHaseth P
J Bacteriol . 2005 Sep; 187(19):6762-9. PMID: 16166539
Upon the exposure of Escherichia coli to high temperature (heat shock), cellular levels of the transcription factor sigma32 rise greatly, resulting in the increased formation of the sigma32 holoenzyme, which...
3.
Probing the role of region 2 of Escherichia coli sigma 70 in nucleation and maintenance of the single-stranded DNA bubble in RNA polymerase-promoter open complexes
deHaseth P, Tsujikawa L
Methods Enzymol . 2004 Jan; 370:553-67. PMID: 14712675
No abstract available.
4.
Differences in replication of a DNA template containing an ethyl phosphotriester by T4 DNA polymerase and Escherichia coli DNA polymerase I
Tsujikawa L, Weinfield M, Reha-Krantz L
Nucleic Acids Res . 2003 Aug; 31(17):4965-72. PMID: 12930945
A DNA template containing a single ethyl phosphotriester was replicated in vitro by the bacteriophage T4 DNA polymerase and by Escherichia coli DNA polymerase I (DNA pol I). Escherichia coli...
5.
RNA polymerase alters the mobility of an A-residue crucial to polymerase-induced melting of promoter DNA
Tsujikawa L, Strainic M, Watrob H, Barkley M, deHaseth P
Biochemistry . 2002 Dec; 41(51):15334-41. PMID: 12484772
Strand separation in promoter DNA induced by Escherichia coli RNA polymerase is likely initiated at a conserved A residue at position -11 of the nontemplate strand. Here we describe the...
6.
Interaction of RNA polymerase with forked DNA: evidence for two kinetically significant intermediates on the pathway to the final complex
Tsujikawa L, Tsodikov O, deHaseth P
Proc Natl Acad Sci U S A . 2002 Mar; 99(6):3493-8. PMID: 11891334
RNA polymerase forms competitor-resistant complexes with "forked DNA" templates that are double-stranded from the -35 promoter region through the first base pair of the -10 region, with an additional unpaired...