Laura Sole
Overview
Explore the profile of Laura Sole including associated specialties, affiliations and a list of published articles.
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36
Citations
577
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Recent Articles
1.
Alonso-Maranon J, Sole L, Alvarez-Villanueva D, Maqueda M, Lobo-Jarne T, Montoto A, et al.
Sci Signal
. 2025 Mar;
18(877):eadr0128.
PMID: 40067909
The DNA damage repair kinase ATM is phosphorylated by the NF-κB pathway kinase IKKα, resulting in enhanced DNA damage repair through the nonhomologous end-joining pathway. Thus, inhibition of IKKα enhances...
2.
Bonfill-Teixidor E, Neva-Alejo A, Arias A, Cuartas I, Iurlaro R, Planas-Rigol E, et al.
Clin Cancer Res
. 2024 Jul;
30(19):4505-4516.
PMID: 39078728
Purpose: Cervical cancer is a viral-associated tumor caused by the infection with the human papilloma virus. Cervical cancer is an immunogenic cancer that expresses viral antigens. Despite being immunogenic, cervical...
3.
Sole L, Lobo-Jarne T, Cabre-Romans J, Gonzalez A, Fernandez L, Marruecos L, et al.
Biochim Biophys Acta Mol Cell Res
. 2024 Jan;
1871(3):119658.
PMID: 38216091
Background: We have previously shown that non-curative chemotherapy imposes fetal conversion and high metastatic capacity to cancer cells. From the set of genes differentially expressed in Chemotherapy Resistant Cells, we...
4.
Pecharroman I, Sole L, Alvarez-Villanueva D, Lobo-Jarne T, Alonso-Maranon J, Bertran J, et al.
EMBO J
. 2023 Sep;
42(21):e114719.
PMID: 37737566
Activation of the IκB kinase (IKK) complex has recurrently been linked to colorectal cancer (CRC) initiation and progression. However, identification of downstream effectors other than NF-κB has remained elusive. Here,...
5.
Bredel M, Espinosa L, Kim H, Scholtens D, McElroy J, Rajbhandari R, et al.
Cell Rep Med
. 2023 Jun;
4(6):101082.
PMID: 37343523
Genetic alterations help predict the clinical behavior of diffuse gliomas, but some variability remains uncorrelated. Here, we demonstrate that haploinsufficient deletions of chromatin-bound tumor suppressor NFKB inhibitor alpha (NFKBIA) display...
6.
Sole L, Lobo-Jarne T, Alvarez-Villanueva D, Alonso-Maranon J, Guillen Y, Guix M, et al.
Nat Commun
. 2022 May;
13(1):2866.
PMID: 35606354
Current therapy against colorectal cancer (CRC) is based on DNA-damaging agents that remain ineffective in a proportion of patients. Whether and how non-curative DNA damage-based treatment affects tumor cell behavior...
7.
Gallardo F, Andrades E, Iglesias A, Gonzalez J, Sole L, Guillen Y, et al.
Blood Adv
. 2022 Apr;
6(11):3410-3421.
PMID: 35413113
Current therapeutic approaches for Sézary syndrome (SS) do not achieve a significant improvement in long-term survival of patients, and they are mainly focused on reducing blood tumor burden to improve...
8.
Vallejo-Gracia A, Sastre D, Colomer-Molera M, Sole L, Navarro-Perez M, Capera J, et al.
Sci Rep
. 2021 Jul;
11(1):14632.
PMID: 34272451
The voltage-dependent potassium channel Kv1.3 plays essential roles in the immune system, participating in leukocyte activation, proliferation and apoptosis. The regulatory subunit KCNE4 acts as an ancillary peptide of Kv1.3,...
9.
Roig S, Sole L, Cassinelli S, Colomer-Molera M, Sastre D, Serrano-Novillo C, et al.
Sci Rep
. 2021 Jul;
11(1):14046.
PMID: 34234241
The voltage-dependent potassium channel Kv1.3 participates in the immune response. Kv1.3 is essential in different cellular functions, such as proliferation, activation and apoptosis. Because aberrant expression of Kv1.3 is linked...
10.
Alonso-Maranon J, Villanueva A, Piulats J, Martinez-Iniesta M, Sole L, Martin-Liberal J, et al.
Oncogene
. 2021 Jun;
40(31):5042-5048.
PMID: 34140639
Invasive malignant melanoma (MM) is an aggressive tumor with no curative therapy in advanced stages. Chemotherapy has not demonstrated its efficacy in MM and current treatment for tumors carrying the...