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Laura Salvini

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Articles 52
Citations 239
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Recent Articles
1.
Frusciante L, Geminiani M, Shabab B, Olmastroni T, Roncucci N, Mastroeni P, et al.
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859264
The sustainable utilization of biomass-derived bioactives addresses the growing demand for natural health products and supports sustainable development goals by reducing reliance on synthetic chemicals in healthcare. biomass, in particular,...
2.
Nardi F, Del Prete R, Drago R, Di Rita A, Vallone F, Ciofini S, et al.
Leukemia . 2024 Oct; 39(1):122-133. PMID: 39443737
Unraveling vulnerabilities in chronic lymphocytic leukemia (CLL) represents a key approach to understand molecular basis for its indolence and a path toward developing tailored therapeutic approaches. In this study, we...
3.
Frusciante L, Geminiani M, Shabab B, Olmastroni T, Scavello G, Rossi M, et al.
Antioxidants (Basel) . 2024 Sep; 13(9). PMID: 39334741
Repurposing saffron () waste presents a sustainable strategy for generating high-value products within the bioeconomy framework. Typically, flower components are discarded after stigma harvest, resulting in significant waste-350 kg of...
4.
Nappini R, Alfini R, Durante S, Salvini L, Raso M, Palmieri E, et al.
Vaccines (Basel) . 2024 Jul; 12(7). PMID: 39066345
Glycoconjugation is a well-established technology for vaccine development: linkage of the polysaccharide (PS) antigen to an appropriate carrier protein overcomes the limitations of PS T-independent antigens, making them effective in...
5.
Frusciante L, Geminiani M, Olmastroni T, Mastroeni P, Trezza A, Salvini L, et al.
Life (Basel) . 2024 Jun; 14(6). PMID: 38929746
The concept of a "circular bioeconomy" holds great promise for the health, cosmetic, and nutrition sectors by re-using (Mill.) by-products. This sustainable resource is rich in bioactive secondary metabolites with...
6.
Frusciante L, Geminiani M, Trezza A, Olmastroni T, Mastroeni P, Salvini L, et al.
Mar Drugs . 2024 May; 22(5). PMID: 38786617
Utilizing plant-based resources, particularly their by-products, aligns with sustainability principles and circular bioeconomy, contributing to environmental preservation. The therapeutic potential of plant extracts is garnering increasing interest, and this study...
7.
Morelli F, Matis S, Benelli R, Salvini L, Zocchi M, Poggi A
Cells . 2024 May; 13(10. PMID: 38786084
Relevant advances have been made in the management of relapsed/refractory (r/r) Hodgkin Lymphomas (HL) with the use of the anti-CD30 antibody-drug conjugate (ADC) brentuximab-vedotin (Bre-Ved). Unfortunately, most patients eventually progress...
8.
Bottoni L, Minetti A, Realini G, Pio E, Giustarini D, Rossi R, et al.
Oncogene . 2024 Apr; 43(22):1701-1713. PMID: 38600165
Triple-negative breast cancer (TNBC) is a very aggressive and heterogeneous group of tumors. In order to develop effective therapeutic strategies, it is therefore essential to identify the subtype-specific molecular mechanisms...
9.
Franci L, Vallini G, Bertolino F, Cicaloni V, Inzalaco G, Cicogni M, et al.
Redox Biol . 2024 Mar; 72:103131. PMID: 38555711
Oxidation processes in mitochondria and different environmental insults contribute to unwarranted accumulation of reactive oxygen species (ROS). These, in turn, rapidly damage intracellular lipids, proteins, and DNA, ultimately causing aging...
10.
Zanardi A, Nardini I, Raia S, Conti A, Ferrini B, DAdamo P, et al.
Commun Biol . 2024 Jan; 7(1):140. PMID: 38291108
Plasma-derived therapeutic proteins are produced through an industrial fractionation process where proteins are purified from individual intermediates, some of which remain unused and are discarded. Relatively few plasma-derived proteins are...