Laura Tinti
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Explore the profile of Laura Tinti including associated specialties, affiliations and a list of published articles.
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22
Citations
232
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Recent Articles
1.
Nardi F, Del Prete R, Drago R, Di Rita A, Vallone F, Ciofini S, et al.
Leukemia
. 2024 Oct;
39(1):122-133.
PMID: 39443737
Unraveling vulnerabilities in chronic lymphocytic leukemia (CLL) represents a key approach to understand molecular basis for its indolence and a path toward developing tailored therapeutic approaches. In this study, we...
2.
Franci L, Vallini G, Bertolino F, Cicaloni V, Inzalaco G, Cicogni M, et al.
Redox Biol
. 2024 Mar;
72:103131.
PMID: 38555711
Oxidation processes in mitochondria and different environmental insults contribute to unwarranted accumulation of reactive oxygen species (ROS). These, in turn, rapidly damage intracellular lipids, proteins, and DNA, ultimately causing aging...
3.
Zanardi A, Nardini I, Raia S, Conti A, Ferrini B, DAdamo P, et al.
Commun Biol
. 2024 Jan;
7(1):140.
PMID: 38291108
Plasma-derived therapeutic proteins are produced through an industrial fractionation process where proteins are purified from individual intermediates, some of which remain unused and are discarded. Relatively few plasma-derived proteins are...
4.
Pasqui A, Cicaloni V, Tinti L, Guiotto A, Tinti C, Mori A, et al.
Arch Biochem Biophys
. 2023 Dec;
752:109860.
PMID: 38110111
Mutations in the X-linked methyl-CpG-binding 2 (MECP2) gene lead to Rett Syndrome (RTT; OMIM 312750), a devasting neurodevelopmental disorder. RTT clinical manifestations are complex and with different degrees of severity,...
5.
Tinti L, Cicaloni V, Nezi P, Isoldi G, Etiope P, Barlozzini B, et al.
Front Plant Sci
. 2023 Apr;
14:1166075.
PMID: 37113593
Hydroxyanthracene derivates (HADs) are a group of natural or synthetic compounds with a wide range of biological activities (for instance, anti-inflammatory, antibacterial, and antiarthritic). In addition, because of their properties...
6.
Laghezza Masci V, Bernini R, Villanova N, Clemente M, Cicaloni V, Tinti L, et al.
Int J Mol Sci
. 2022 Oct;
23(20).
PMID: 36293207
The antitumor activity of polyphenols derived from extra virgin olive oil and, in particular the biological activity of HTyr, has been studied extensively. However, the use of HTyr as a...
7.
Barbera S, Raucci L, Tassone G, Tinti L, Prischi F, Santucci A, et al.
Int J Biol Macromol
. 2022 Oct;
224:453-464.
PMID: 36265539
Blocking the signaling activated by the plasma membrane receptor CD93 has recently been demonstrated a useful tool in antiangiogenic treatment and oncotherapy. In the proliferating endothelium, CD93 regulates cell adhesion,...
8.
Grieco G, Brusco N, Fignani D, Nigi L, Formichi C, Licata G, et al.
Cell Death Discov
. 2022 Jul;
8(1):340.
PMID: 35906204
The loss of functional β-cell mass in type 2 diabetes (T2D) is associated with molecular events that include β-cell apoptosis, dysfunction and/or dedifferentiation. MicroRNA miR-184-3p has been shown to be...
9.
Galderisi S, Milella M, Rossi M, Cicaloni V, Rossi R, Giustarini D, et al.
Arch Biochem Biophys
. 2022 Jan;
717:109137.
PMID: 35090868
Alkaptonuria (AKU) is an ultra-rare genetic disease caused by a deficient activity of the enzyme homogentisate 1,2-dioxygenase (HGD) leading to the accumulation of homogentisic acid (HGA) on connective tissues. Even...
10.
Homogentisic acid induces cytoskeleton and extracellular matrix alteration in alkaptonuric cartilage
Galderisi S, Cicaloni V, Milella M, Millucci L, Geminiani M, Salvini L, et al.
J Cell Physiol
. 2021 Jan;
236(8):6011-6024.
PMID: 33469937
Alkaptonuria (AKU) is an ultra-rare disease caused by the deficient activity of homogentisate 1,2-dioxygenase enzyme, leading the accumulation of homogentisic acid (HGA) in connective tissues implicating the formation of a...