Laura E McBreairty
Overview
Explore the profile of Laura E McBreairty including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
199
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0
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Recent Articles
11.
Robinson J, McBreairty L, Randell E, Brunton J, Bertolo R
J Nutr Biochem
. 2016 Jul;
35:81-86.
PMID: 27469995
Methionine is required for protein synthesis and provides a methyl group for >50 critical transmethylation reactions including creatine and phosphatidylcholine synthesis as well as DNA and protein methylation. However, the...
12.
McBreairty L
Appl Physiol Nutr Metab
. 2016 May;
41(6):691.
PMID: 27207152
Methionine is an essential amino acid which when not incorporated into protein, can be converted to S-adenosylmethionine, the universal methyl donor in over 200 transmethylation reactions, which include creatine and...
13.
McBreairty L, Bertolo R
Appl Physiol Nutr Metab
. 2016 May;
41(6):581-7.
PMID: 27177124
Methionine is an indispensable amino acid that, when not incorporated into protein, is converted into the methyl donor S-adenosylmethionine as entry into the methionine cycle. Following transmethylation, homocysteine is either...
14.
McBreairty L, Robinson J, Harding S, Randell E, Brunton J, Bertolo R
Eur J Nutr
. 2015 Oct;
55(8):2423-2430.
PMID: 26419586
Purpose: Both folate and betaine (synthesized from choline) are nutrients used to methylate homocysteine to reform the amino acid methionine following donation of its methyl group; however, it is unclear...
15.
McBreairty L, Robinson J, Furlong K, Brunton J, Bertolo R
PLoS One
. 2015 Jun;
10(6):e0131563.
PMID: 26110793
Creatine (Cr) is an important high-energy phosphate buffer in tissues with a high energy demand such as muscle and brain and is consequently a highly consumed nutritional supplement. Creatine is...
16.
McBreairty L, McGowan R, Brunton J, Bertolo R
J Nutr
. 2013 Apr;
143(6):804-9.
PMID: 23616507
Methionine is the main source of methyl groups that are partitioned to synthesize various methylated products including creatine, phosphatidylcholine (PC), and methylated DNA. Whether increased methylation of 1 product can...
17.
Bertolo R, McBreairty L
Curr Opin Clin Nutr Metab Care
. 2012 Dec;
16(1):102-8.
PMID: 23196816
Purpose Of Review: Methyl group metabolism is a metabolically demanding process that has significant nutritional implications. Methionine is required not only for protein synthesis but also as the primary source...
18.
MacKay D, Brophy J, McBreairty L, McGowan R, Bertolo R
J Nutr Biochem
. 2011 Dec;
23(9):1121-7.
PMID: 22137257
Intrauterine growth restriction (IUGR), in both animals and humans, has been linked to metabolic syndrome later in life. There has been recent evidence that perturbations in sulfur amino acid metabolism...