Laura Bizzozero
Overview
Explore the profile of Laura Bizzozero including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
193
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Recent Articles
1.
Agostini A, Guerriero I, Piro G, Quero G, Roberto L, Esposito A, et al.
J Transl Med
. 2023 Nov;
21(1):843.
PMID: 37996891
Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. This is due to its aggressive course, late diagnosis and its intrinsic drugs resistance. The complexity of the tumor, in terms...
2.
Arese M, Bussolino F, Pergolizzi M, Bizzozero L
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499024
We propose an overview of the molecular cues and their intracellular signaling involved in the crosstalk between cancer and the nervous system. While "cancer neuroscience" as a field is still...
3.
Pergolizzi M, Bizzozero L, Maione F, Maldi E, Isella C, Macagno M, et al.
J Exp Clin Cancer Res
. 2022 Sep;
41(1):266.
PMID: 36056393
Background: Colorectal cancer (CRC) remains largely incurable when diagnosed at the metastatic stage. Despite some advances in precision medicine for this disease in recent years, new molecular targets, as well...
4.
Bizzozero L, Pergolizzi M, Pascal D, Maldi E, Villari G, Erriquez J, et al.
Cells
. 2022 Jan;
11(2).
PMID: 35053395
Many nervous proteins are expressed in cancer cells. In this report, we asked whether the synaptic protein neuroligin 1 (NLGN1) was expressed by prostatic and pancreatic carcinomas; in addition, given...
5.
Pergolizzi M, Bizzozero L, Riccitelli E, Pascal D, Samarelli A, Bussolino F, et al.
Biochem Biophys Res Commun
. 2018 May;
501(1):165-171.
PMID: 29709479
The synaptic protein Neuroligin 2, similarly to its isoform Neuroligin 1, is produced by endothelial cells, but its activity in the vascular context remains unknown. This study aimed at verifying...
6.
Arese M, Bussolino F, Pergolizzi M, Bizzozero L, Pascal D
Ann Transl Med
. 2018 Apr;
6(5):89.
PMID: 29666812
One of the challenges of cancer is its heterogeneity and rapid capacity to adapt. Notwithstanding significant progress in the last decades in genomics and precision medicine, new molecular targets and...
7.
Cervia D, Assi E, De Palma C, Giovarelli M, Bizzozero L, Pambianco S, et al.
Oncotarget
. 2016 Apr;
7(18):24995-5009.
PMID: 27107419
The sphingolipid metabolising enzyme Acid Sphingomyelinase (A-SMase) has been recently shown to inhibit melanoma progression and correlate inversely to tumour grade. In this study we have investigated the role of...
8.
Assi E, Cervia D, Bizzozero L, Capobianco A, Pambianco S, Morisi F, et al.
Mediators Inflamm
. 2015 Jun;
2015:370482.
PMID: 26101462
The inflammatory microenvironment induces tumours to acquire an aggressive and immunosuppressive behaviour. Since acid sphingomyelinase (A-SMase) downregulation in melanoma was shown to determine a malignant phenotype, we aimed here to...
9.
Samarelli A, Riccitelli E, Bizzozero L, Silveira T, Seano G, Pergolizzi M, et al.
J Biol Chem
. 2014 May;
289(28):19466-76.
PMID: 24860089
The synaptic protein Neuroligin 1 (NLGN1), a cell adhesion molecule, is critical for the formation and consolidation of synaptic connectivity and is involved in vascular development. The mechanism through which...
10.
Perrotta C, Bizzozero L, Cazzato D, Morlacchi S, Assi E, Simbari F, et al.
J Biol Chem
. 2010 Oct;
285(51):40240-51.
PMID: 20956541
Acid sphingomyelinase (A-SMase) is an important enzyme in sphingolipid metabolism and plays key roles in apoptosis, immunity, development, and cancer. In addition, it mediates cytotoxicity of cisplatin and some other...