Laszlo Homolya
Overview
Explore the profile of Laszlo Homolya including associated specialties, affiliations and a list of published articles.
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Articles
68
Citations
1216
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Recent Articles
1.
Jezso B, Kalman S, Farkas K, Hathy E, Vincze K, Kovacs-Schoblocher D, et al.
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927091
Background: Induced pluripotent stem cell (iPSC) based neuronal differentiation is valuable for studying neuropsychiatric disorders and pharmacological mechanisms at the cellular level. We aimed to examine the effects of typical...
2.
Tordai C, Hathy E, Gyergyak H, Vincze K, Baradits M, Koller J, et al.
Schizophr Res
. 2024 Jan;
273:107-120.
PMID: 38290943
Background: Schizophrenia (SCZ) is a severe neuropsychiatric disorder of complex, poorly understood etiology, associated with both genetic and environmental factors. De novo mutations (DNMs) represent a new source of genetic...
3.
Mozner O, Zambo B, Bartos Z, Gergely A, Szabo K, Jezso B, et al.
Membranes (Basel)
. 2023 Oct;
13(10).
PMID: 37887994
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this...
4.
Gyongy Z, Mocsar G, Hegedus E, Stockner T, Ritter Z, Homolya L, et al.
Elife
. 2023 Feb;
12.
PMID: 36763413
ABCG2 is an exporter-type ABC protein that can expel numerous chemically unrelated xeno- and endobiotics from cells. When expressed in tumor cells or tumor stem cells, ABCG2 confers multidrug resistance,...
5.
Hegyi Z, Hegedus T, Homolya L
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430223
ABCG1 has been proposed to play a role in HDL-dependent cellular sterol regulation; however, details of the interaction between the transporter and its potential sterol substrates have not been revealed....
6.
Lilienberg J, Apati A, Rethelyi J, Homolya L
Front Cell Dev Biol
. 2022 Oct;
10:997028.
PMID: 36313581
Microglia, the primary immune cells of the brain, significantly influence the fate of neurons after neural damage. Depending on the local environment, they exhibit a wide range of phenotypes, including...
7.
Lazar B, Szabadi N, Anand M, Toth R, Ecker A, Urban M, et al.
Genes (Basel)
. 2022 Jan;
13(1).
PMID: 35052421
The primordial germ cells (PGCs) are the precursors for both the oocytes and spermatogonia. Recently, a novel culture system was established for chicken PGCs, isolated from embryonic blood. The possibility...
8.
Lilienberg J, Hegyi Z, Szabo E, Hathy E, Malnasi-Csizmadia A, Rethelyi J, et al.
Front Cell Dev Biol
. 2021 Oct;
9:719636.
PMID: 34604221
Studies on neural development and neuronal regeneration after injury are mainly based on animal models. The establishment of pluripotent stem cell (PSC) technology, however, opened new perspectives for better understanding...
9.
Szabo E, Juhasz F, Homolya L, Erdei Z, Apati A
Methods Mol Biol
. 2021 Apr;
2454:241-255.
PMID: 33826126
Human neuronal cell cultures are essential tools for biological and preclinical studies of our nervous system. Since we have very limited access to primary human neural samples, derivation of proliferative...
10.
Naffa R, Padanyi R, Ignacz A, Hegyi Z, Jezso B, Toth S, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33802790
We demonstrated that the plasma membrane Ca ATPase PMCA4b inhibits migration and metastatic activity of BRAF mutant melanoma cells. Actin dynamics are essential for cells to move, invade and metastasize,...