Lars Mitschke
Overview
Explore the profile of Lars Mitschke including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
160
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0
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Recent Articles
1.
Mitschke L, Parthier C, Schroder-Tittmann K, Coy J, Ludtke S, Tittmann K
J Biol Chem
. 2010 Jul;
285(41):31559-70.
PMID: 20667822
The crystal structure of human transketolase (TKT), a thiamine diphosphate (ThDP) and Ca(2+)-dependent enzyme that catalyzes the interketol transfer between ketoses and aldoses as part of the pentose phosphate pathway,...
2.
Retzlaff M, Hagn F, Mitschke L, Hessling M, Gugel F, Kessler H, et al.
Mol Cell
. 2010 Feb;
37(3):344-54.
PMID: 20159554
The chaperone Hsp90 is an ATP-dependent, dimeric molecular machine regulated by several cochaperones, including inhibitors and the unique ATPase activator Aha1. Here, we analyzed the mechanism of the Aha1-mediated acceleration...