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» Authors » Lara M Taubner

Lara M Taubner

Explore the profile of Lara M Taubner including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 449
Followers 0
Related Specialties
Biochemistry
Microbiology
Molecular Biology
Top 10 Co-Authors
Valerie Copie
Byron Caughey
David M Dooley
Michele A McGuirl
Christina D Orru
Brent Race
Allison Kraus
Suzette A Priola
Kimberly D Meade-White
Roger A Moore
Published In
J Biomol NMR
J Mol Biol
Biochemistry
PLoS Pathog
Curr Opin Struct Biol
Affiliations
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Recent Articles
1.
Parallel in-register intermolecular β-sheet architectures for prion-seeded prion protein (PrP) amyloids
Groveman B, Dolan M, Taubner L, Kraus A, Wickner R, Caughey B
J Biol Chem . 2014 Jul; 289(35):24129-42. PMID: 25028516
Structures of the infectious form of prion protein (e.g. PrP(Sc) or PrP-Scrapie) remain poorly defined. The prevalent structural models of PrP(Sc) retain most of the native α-helices of the normal,...
2.
Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays
Wilham J, Orru C, Bessen R, Atarashi R, Sano K, Race B, et al.
PLoS Pathog . 2010 Dec; 6(12):e1001217. PMID: 21152012
A major problem for the effective diagnosis and management of prion diseases is the lack of rapid high-throughput assays to measure low levels of prions. Such measurements have typically required...
3.
Structure of the flexible amino-terminal domain of prion protein bound to a sulfated glycan
Taubner L, Bienkiewicz E, Copie V, Caughey B
J Mol Biol . 2009 Nov; 395(3):475-90. PMID: 19913031
The intrinsically disordered amino-proximal domain of hamster prion protein (PrP) contains four copies of a highly conserved octapeptide sequence, PHGGGWGQ, that is flanked by two polycationic residue clusters. This N-terminal...
4.
Prion protein misfolding and disease
Moore R, Taubner L, Priola S
Curr Opin Struct Biol . 2009 Jan; 19(1):14-22. PMID: 19157856
Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and other mammals. TSEs are protein misfolding diseases that involve the...
5.
Structural studies of Apo NosL, an accessory protein of the nitrous oxide reductase system: insights from structural homology with MerB, a mercury resistance protein
Taubner L, McGuirl M, Dooley D, Copie V
Biochemistry . 2006 Oct; 45(40):12240-52. PMID: 17014077
The formation of the unique catalytic tetranuclear copper cluster (Cu(Z)) of nitrous oxide reductase, N(2)OR, requires the coexpression of a multiprotein assembly apparatus encoded by the nosDFYL operon. NosL, one...
6.
1H, 13C, 15N backbone and sidechain resonance assignments of apo-NosL, a novel copper(I) binding protein from the nitrous oxide reductase gene cluster of Achromobacter cycloclastes
Taubner L, McGuirl M, Dooley D, Copie V
J Biomol NMR . 2004 Mar; 29(2):211-2. PMID: 15014237
No abstract available.