Lara A Muffley
Overview
Explore the profile of Lara A Muffley including associated specialties, affiliations and a list of published articles.
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26
Citations
472
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0
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Recent Articles
1.
Dawood M, Fayer S, Pendyala S, Post M, Kalra D, Patterson K, et al.
Genome Med
. 2024 Dec;
16(1):143.
PMID: 39627863
Background: Multiplexed Assays of Variant Effects (MAVEs) can test all possible single variants in a gene of interest. The resulting saturation-style functional data may help resolve variant classification disparities between...
2.
Dawood M, Fayer S, Pendyala S, Post M, Kalra D, Patterson K, et al.
medRxiv
. 2024 Apr;
PMID: 38645101
Background: Multiplexed Assays of Variant Effects (MAVEs) can test all possible single variants in a gene of interest. The resulting saturation-style data may help resolve variant classification disparities between populations,...
3.
Claussnitzer M, Parikh V, Wagner A, Arbesfeld J, Bult C, Firth H, et al.
Genome Biol
. 2024 Apr;
25(1):100.
PMID: 38641812
Multiplexed assays of variant effect (MAVEs) have emerged as a powerful approach for interrogating thousands of genetic variants in a single experiment. The flexibility and widespread adoption of these techniques...
4.
Claussnitzer M, Parikh V, Wagner A, Arbesfeld J, Bult C, Firth H, et al.
ArXiv
. 2023 Jul;
PMID: 37426450
Multiplexed Assays of Variant Effect (MAVEs) have emerged as a powerful approach for interrogating thousands of genetic variants in a single experiment. The flexibility and widespread adoption of these techniques...
5.
Fowler D, Adams D, Gloyn A, Hahn W, Marks D, Muffley L, et al.
Genome Biol
. 2023 Jul;
24(1):147.
PMID: 37394429
Sequencing has revealed hundreds of millions of human genetic variants, and continued efforts will only add to this variant avalanche. Insufficient information exists to interpret the effects of most variants,...
6.
Kneib C, Sibbett S, Carrougher G, Muffley L, Gibran N, Mandell S
J Burn Care Res
. 2019 Mar;
40(4):457-463.
PMID: 30893433
Gabapentin has analgesic efficacy for neuropathic pain and is increasingly used in burn care. This study investigated the effect of a neuropathic pain control protocol, as well as early gabapentin...
7.
Carter D, Sood R, Seaton M, Muffley L, Honari S, Hocking A, et al.
J Surg Res
. 2018 Oct;
231:448-452.
PMID: 30278967
Background: Systemic inflammatory response syndrome (SIRS) is associated with organ failure and infectious complications after major burn injury. Recent evidence has linked melanocortin signaling to anti-inflammatory and wound-repair functions, with...
8.
Carrougher G, Muffley L, Baker C, Gibran N
J Burn Care Res
. 2018 Jun;
39(5):786-789.
PMID: 29931107
Successful acquisition of survey data in any longitudinal study is key to reducing bias and determining reliable, generalizable findings. As part of a multicenter longitudinal study of patient-reported outcomes, a...
9.
Seaton M, Parent B, Sood R, Wurfel M, Muffley L, OKeefe G, et al.
Shock
. 2016 Aug;
47(1):79-85.
PMID: 27488084
Objective: The aim of the study was to determine if melanocortin-1 receptor (MC1R) single nucleotide polymorphisms (SNPs) are associated with complicated sepsis after trauma. Background: Nosocomial infections are an important...
10.
Sood R, Muffley L, Seaton M, Ga M, Sirimahachaiyakul P, Hocking A, et al.
Plast Reconstr Surg
. 2015 Oct;
136(5):990-1000.
PMID: 26505702
Background: The pathophysiology of hypertrophic scarring is unknown in part because of the lack of a robust animal model. Although the red Duroc pig has emerged as a promising in...