Lap Ping Chung
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Explore the profile of Lap Ping Chung including associated specialties, affiliations and a list of published articles.
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12
Citations
443
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Recent Articles
1.
Blechter B, Hsiung C, Wang X, Zhang H, Seow W, Shi J, et al.
J Thorac Oncol
. 2024 Nov;
PMID: 39581378
We assessed the association between a genome-wide polygenic risk score (PRS) developed for lung adenocarcinoma (LUAD) risk and mutation on the EGFR gene in 998 East Asian never-smoking female LUAD...
2.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, et al.
medRxiv
. 2024 Jul;
PMID: 38978671
Polygenic risk scores (PRSs) are promising for risk stratification but have mainly been developed in European populations. This study developed single- and multi-ancestry PRSs for lung adenocarcinoma (LUAD) in East...
3.
Shi J, Shiraishi K, Choi J, Matsuo K, Chen T, Dai J, et al.
Nat Commun
. 2023 May;
14(1):3043.
PMID: 37236969
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study...
4.
Wong J, Zhang H, Hsiung C, Shiraishi K, Yu K, Matsuo K, et al.
Genomics
. 2019 Jul;
112(2):1223-1232.
PMID: 31306748
We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway...
5.
Seow W, Matsuo K, Hsiung C, Shiraishi K, Song M, Kim H, et al.
Hum Mol Genet
. 2016 Dec;
26(2):454-465.
PMID: 28025329
To evaluate associations by EGFR mutation status for lung adenocarcinoma risk among never-smoking Asian women, we conducted a meta-analysis of 11 loci previously identified in genome-wide association studies (GWAS). Genotyping...
6.
Wong K, So C, Loong F, Chung L, Lam W, Liang R, et al.
PLoS One
. 2011 May;
6(4):e19027.
PMID: 21544199
miR-124-1 is a tumour suppressor microRNA (miR). Epigenetic deregulation of miRs is implicated in carcinogenesis. Promoter DNA methylation and histone modification of miR-124-1 was studied in 5 normal marrow controls,...
7.
Chim C, Wong K, Leung C, Chung L, Hui P, Chan S, et al.
J Cell Mol Med
. 2011 Feb;
15(12):2760-7.
PMID: 21323860
miR-203 is a tumour suppressor microRNA (miRNA). We studied the methylation of hsa-miR-203 in 150 samples including acute myeloid leukaemia (AML), acute lymphoblastic leukaemia (ALL), chronic myeloid leukaemia (CML), chronic...
8.
Tam I, Chung L, Suen W, Wang E, Wong M, Ho K, et al.
Clin Cancer Res
. 2006 Mar;
12(5):1647-53.
PMID: 16533793
Purpose: This study evaluated the mutational profile of epidermal growth factor receptor (EGFR) and KRAS in non-small cell lung cancers in Hong Kong and determined their relation with smoking history...
9.
Zhu H, Lam D, Han K, Tin V, Suen W, Wang E, et al.
Cancer Lett
. 2006 Mar;
245(1-2):303-14.
PMID: 16517066
Tumours develop from clonally expanded population of cells harbouring aberrations of oncogenes and tumour suppressor genes. In this study, metaphase and array comparative genomic hybridization showed good correlation of aberration...
10.
Yap Y, Lam D, Luc G, Zhang X, Hernandez D, Gras R, et al.
Nucleic Acids Res
. 2005 Jan;
33(1):409-21.
PMID: 15653641
Gene transcription in a set of 49 human primary lung adenocarcinomas and 9 normal lung tissue samples was examined using Affymetrix GeneChip technology. A total of 3442 genes, called the...