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Lanfei Feng

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Articles 9
Citations 76
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Li F, Bahnson E, Wilder J, Siletzky R, Hagaman J, Nickekeit V, et al.
Redox Biol . 2020 Mar; 32:101504. PMID: 32182573
Renal ischemia/reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI), a potentially fatal syndrome characterized by a rapid decline in kidney function. Excess production of superoxide contributes...
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Feng L, Vujicic S, Dietrich M, Litbarg N, Setty S, Antoni A, et al.
J Biol Chem . 2018 May; 293(26):10245-10263. PMID: 29769319
The consequences of apoptosis extend beyond the mere death of the cell. We have shown that receptor-mediated recognition of apoptotic target cells by viable kidney proximal tubular epithelial cells (PTECs)...
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Vujicic S, Feng L, Antoni A, Rauch J, Levine J
J Vis Exp . 2017 Jan; (118). PMID: 28060335
Cells dying by apoptosis, also referred to as regulated cell death, acquire multiple new activities that enable them to influence the function of adjacent live cells. Vital activities, such as...
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Patel V, Massenburg D, Vujicic S, Feng L, Tang M, Litbarg N, et al.
J Biol Chem . 2015 Jul; 290(37):22352-69. PMID: 26183782
Apoptosis plays an indispensable role in the maintenance and development of tissues. We have shown that receptor-mediated recognition of apoptotic target cells by viable kidney proximal tubular epithelial cells (PTECs)...
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Patel V, Feng L, Lee D, Massenburg D, Pattabiraman G, Antoni A, et al.
J Biol Chem . 2012 Mar; 287(17):13761-77. PMID: 22396534
Apoptosis allows for the removal of damaged, aged, and/or excess cells without harm to surrounding tissue. To accomplish this, cells undergoing apoptosis acquire new activities that enable them to modulate...
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Patel V, Lee D, Feng L, Antoni A, Lieberthal W, Schwartz J, et al.
J Biol Chem . 2009 Nov; 285(3):1829-40. PMID: 19910463
During apoptosis, cells acquire new activities that enable them to modulate the fate and function of interacting phagocytes, particularly macrophages (m). Although the best known of these activities is anti-inflammatory,...
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Patel V, Lee D, Longacre-Antoni A, Feng L, Lieberthal W, Rauch J, et al.
Autoimmunity . 2009 Oct; 42(4):317-21. PMID: 19811288
Virtually all cells in the body have the capacity to recognize and respond to dead cells. Viable cells discriminate apo from nec targets via distinct cell surface receptors. Engagement of...
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Patel V, Longacre-Antoni A, Cvetanovic M, Lee D, Feng L, Fan H, et al.
Autoimmunity . 2007 May; 40(4):274-80. PMID: 17516209
Growing evidence exists for a new role for apoptotic cell recognition and clearance in immune homeostasis. Apoptotic cells at all stages, irrespective of membrane integrity, elicit a signature set of...