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Lance P Encell

Explore the profile of Lance P Encell including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 2953
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Recent Articles
1.
Gaspar N, Handula M, Stroet M, Marella-Panth K, Haeck J, Kirkland T, et al.
Int J Mol Sci . 2024 Aug; 25(15). PMID: 39125775
Multimodality reporter gene imaging combines the sensitivity, resolution and translational potential of two or more signals. The approach has not been widely adopted by the animal imaging community, mainly because...
2.
Shakhova E, Karataeva T, Markina N, Mitiouchkina T, Palkina K, Perfilov M, et al.
Nat Methods . 2024 Jan; 21(3):406-410. PMID: 38253843
The discovery of the bioluminescence pathway in the fungus Neonothopanus nambi enabled engineering of eukaryotes with self-sustained luminescence. However, the brightness of luminescence in heterologous hosts was limited by performance...
3.
Su Y, Walker J, Hall M, Klein M, Wu X, Encell L, et al.
Nat Chem Biol . 2023 Feb; 19(6):731-739. PMID: 36759751
Bioluminescence imaging (BLI) allows non-invasive visualization of cells and biochemical events in vivo and thus has become an indispensable technique in biomedical research. However, BLI in the central nervous system...
4.
Torio E, Ressler V, Kincaid V, Hurst R, Hall M, Encell L, et al.
Front Microbiol . 2022 Nov; 13:970233. PMID: 36386626
Point-of-care tests are highly valuable in providing fast results for medical decisions for greater flexibility in patient care. Many diagnostic tests, such as ELISAs, that are commonly used within clinical...
5.
Kincaid V, Wang H, Sondgeroth C, Torio E, Ressler V, Fitzgerald C, et al.
ACS Chem Biol . 2022 Jul; 17(8):2179-2187. PMID: 35862857
Sensitive and selective detection assays are essential for the accurate measurement of analytes in both clinical and research laboratories. Immunoassays that rely on nonoverlapping antibodies directed against the same target...
6.
Hall M, Kincaid V, Jost E, Smith T, Hurst R, Forsyth S, et al.
Anal Chem . 2021 Mar; 93(12):5177-5184. PMID: 33730483
Enzyme-linked immunosorbent assays (ELISAs) are used extensively for the detection and quantification of biomolecules in clinical diagnostics as well as in basic research. Although broadly used, the inherent complexities of...
7.
Zambito G, Hall M, Wood M, Gaspar N, Ridwan Y, Stellari F, et al.
iScience . 2021 Jan; 24(1):101986. PMID: 33490896
For multicolor bioluminescence applications, red and near-infrared signals are desirable over shorter wavelength signals because they are not as susceptible to light attenuation by blood and tissue. Herein, we describe...
8.
Shi C, Killoran M, Hall M, Otto P, Wood M, Strauss E, et al.
PLoS One . 2020 Dec; 15(12):e0243747. PMID: 33315907
Firefly luciferase-based ATP detection assays are frequently used as a sensitive, cost-efficient method for monitoring hygiene in many industrial settings. Solutions of detection reagent, containing a mixture of a substrate...
9.
Zambito G, Gaspar N, Ridwan Y, Hall M, Shi C, Kirkland T, et al.
Mol Imaging Biol . 2020 Sep; 22(6):1523-1531. PMID: 32926287
Purpose: Currently, a variety of red and green beetle luciferase variants are available for bioluminescence imaging (BLI). In addition, new luciferin analogues providing longer wavelength luminescence have been developed that...
10.
Su Y, Walker J, Park Y, Smith T, Liu L, Hall M, et al.
Nat Methods . 2020 Jul; 17(8):852-860. PMID: 32661427
Sensitive detection of two biological events in vivo has long been a goal in bioluminescence imaging. Antares, a fusion of the luciferase NanoLuc to the orange fluorescent protein CyOFP, has...