Lan V Zhang
Overview
Explore the profile of Lan V Zhang including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
3870
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Suzuki Y, St Onge R, Mani R, King O, Heilbut A, Labunskyy V, et al.
Nat Methods
. 2011 Jan;
8(2):159-64.
PMID: 21217751
Phenotypes that might otherwise reveal a gene's function can be obscured by genes with overlapping function. This phenomenon is best known within gene families, in which an important shared function...
2.
Tian W, Zhang L, Tasan M, Gibbons F, King O, Park J, et al.
Genome Biol
. 2008 Jul;
9 Suppl 1:S7.
PMID: 18613951
Background: Learning the function of genes is a major goal of computational genomics. Methods for inferring gene function have typically fallen into two categories: 'guilt-by-profiling', which exploits correlation between function...
3.
Rual J, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al.
Nature
. 2005 Sep;
437(7062):1173-8.
PMID: 16189514
Systematic mapping of protein-protein interactions, or 'interactome' mapping, was initiated in model organisms, starting with defined biological processes and then expanding to the scale of the proteome. Although far from...
4.
Wong S, Zhang L, Roth F
Trends Genet
. 2005 Jun;
21(8):424-7.
PMID: 15982781
Biochemists and geneticists, represented by Doug and Bill in classic essays, have long debated the merits of their methods. We revisited this issue using genomic data from the budding yeast,...
5.
Zhang L, King O, Wong S, Goldberg D, Tong A, Lesage G, et al.
J Biol
. 2005 Jun;
4(2):6.
PMID: 15982408
Background: Large-scale studies have revealed networks of various biological interaction types, such as protein-protein interaction, genetic interaction, transcriptional regulation, sequence homology, and expression correlation. Recurring patterns of interconnection, or 'network...
6.
Wong S, Zhang L, Tong A, Li Z, Goldberg D, King O, et al.
Proc Natl Acad Sci U S A
. 2004 Oct;
101(44):15682-7.
PMID: 15496468
Genetic interactions define overlapping functions and compensatory pathways. In particular, synthetic sick or lethal (SSL) genetic interactions are important for understanding how an organism tolerates random mutation, i.e., genetic robustness....
7.
Han J, Bertin N, Hao T, Goldberg D, Berriz G, Zhang L, et al.
Nature
. 2004 Jun;
430(6995):88-93.
PMID: 15190252
In apparently scale-free protein-protein interaction networks, or 'interactome' networks, most proteins interact with few partners, whereas a small but significant proportion of proteins, the 'hubs', interact with many partners. Both...
8.
Zhang L, Wong S, King O, Roth F
BMC Bioinformatics
. 2004 Apr;
5:38.
PMID: 15090078
Background: Identifying all protein-protein interactions in an organism is a major objective of proteomics. A related goal is to know which protein pairs are present in the same protein complex....
9.
Tong A, Lesage G, Bader G, Ding H, Xu H, Xin X, et al.
Science
. 2004 Feb;
303(5659):808-13.
PMID: 14764870
A genetic interaction network containing approximately 1000 genes and approximately 4000 interactions was mapped by crossing mutations in 132 different query genes into a set of approximately 4700 viable gene...
10.
Li S, Armstrong C, Bertin N, Ge H, Milstein S, Boxem M, et al.
Science
. 2004 Jan;
303(5657):540-3.
PMID: 14704431
To initiate studies on how protein-protein interaction (or "interactome") networks relate to multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans interactome network. Starting with a subset...