Lalit R Patel
Overview
Explore the profile of Lalit R Patel including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
1014
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Recent Articles
1.
McDaniel J, Morrissey R, Dibra D, Patel L, Xiong S, Zhang Y, et al.
Cancer Res Commun
. 2024 Jul;
4(8):1991-2007.
PMID: 38994678
Significance: Our findings implicate NR5A2 as a novel mediator of mutant p53 transcriptional activity in breast cancer. NR5A2 may be an important therapeutic target in hard-to-treat breast cancers such as...
2.
Patel L, Stratton S, McLaughlin M, Krause P, Allton K, Rivas A, et al.
iScience
. 2023 Jul;
26(7):107126.
PMID: 37426340
is an oncogenic chromatin reader that is frequently overexpressed in human tumors and associated with poor prognosis. However, is rarely mutated, duplicated, or rearranged in cancer. This raises questions about...
3.
Chachad D, Patel L, Recio C, Pourebrahim R, Whitley E, Wang W, et al.
Cancer Res
. 2023 May;
83(14):2297-2311.
PMID: 37205631
Significance: The p53 DNA binding domain contact mutant p53R245W, but not the structural mutant p53R172H, interacts with KLF15 to drive metastasis in somatic osteosarcoma, providing a potential vulnerability in tumors...
4.
Jain A, Xi Y, McCarthy R, Allton K, Akdemir K, Patel L, et al.
Mol Cell
. 2016 Dec;
64(5):967-981.
PMID: 27912097
Recent evidence suggests that lncRNAs play an integral regulatory role in numerous functions, including determination of cellular identity. We determined global expression (RNA-seq) and genome-wide profiles (ChIP-seq) of histone post-translational...
5.
Sircar K, Yoo S, Majewski T, Wani K, Patel L, Voicu H, et al.
J Pathol Clin Res
. 2016 Aug;
1(4):212-24.
PMID: 27499906
Sarcomatoid transformation, wherein an epithelioid carcinomatous tumour component coexists with a sarcomatoid histology, is a predictor of poor prognosis in clear cell renal cell carcinoma. Our understanding of sarcomatoid change...
6.
Patel L, Barton M
Cancer Cell
. 2016 Jun;
29(6):776-778.
PMID: 27300431
Prostate cancer is lethal when tumors evolve to activate androgen receptor signaling, which circumvents ligand-deprivation therapy. In this issue of Cancer Cell, Groner et al. show that histone reader and...
7.
Singh R, Murugan P, Patel L, Voicu H, Yoo S, Majewski T, et al.
Mod Pathol
. 2015 Jun;
28(9):1225-35.
PMID: 26111976
Rhabdoid histology in clear-cell renal cell carcinoma is associated with a poor prognosis. The prognosis of patients with clear-cell renal cell carcinoma may also be influenced by molecular alterations. The...
8.
Taichman R, Patel L, Bedenis R, Wang J, Weidner S, Schumann T, et al.
PLoS One
. 2013 May;
8(4):e61873.
PMID: 23637920
Disseminated tumor cells (DTCs) are believed to lie dormant in the marrow before they can be activated to form metastases. How DTCs become dormant in the marrow and how dormant...
9.
Patel L, Nykter M, Chen K, Zhang W
Cancer Lett
. 2012 Nov;
340(2):152-60.
PMID: 23111104
Advances in cancer genomics have been propelled by the steady evolution of molecular profiling technologies. Over the past decade, high-throughput sequencing technologies have matured to the point necessary to support...
10.
Hsiao A, Tung Y, Qu X, Patel L, Pienta K, Takayama S
Biotechnol Bioeng
. 2011 Dec;
109(5):1293-304.
PMID: 22161651
We previously reported the development of a simple, user-friendly, and versatile 384 hanging drop array plate for 3D spheroid culture and the importance of utilizing 3D cellular models in anti-cancer...