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Lakshmi S Nair

Explore the profile of Lakshmi S Nair including associated specialties, affiliations and a list of published articles. Areas
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Articles 91
Citations 2236
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Recent Articles
1.
Kishnan D, Morato E, Calsetta A, Baumbauer K, Nair L
Life (Basel) . 2024 Aug; 14(8). PMID: 39202725
Pain is the primary clinical indication of osteoarthritis (OA), and behavioral assessments in rodent pain models are widely used to understand pain patterns. These preclinical pain assessments can also help...
2.
Morato E, Knight B, Nair L
In Vitro Model . 2023 Dec; 1(4-5):385-395. PMID: 38107764
Pathological pain is a prevalent condition that affects majority of adults with a variety of underlying disease conditions. Current available pharmacological pain treatments have several negative and potentially life-threatening side...
3.
Saveh-Shemshaki N, Barajaa M, Otsuka T, Mirdamadi E, Nair L, Laurencin C
Regen Biomater . 2023 Nov; 10:rbad099. PMID: 38020235
Muscle degeneration is one the main factors that lead to the high rate of retear after a successful repair of rotator cuff (RC) tears. The current surgical practices have failed...
4.
Ude C, Schmidt S, Laurencin S, Shah S, Esdaille J, Kan H, et al.
Proc Natl Acad Sci U S A . 2023 Oct; 120(45):e2309156120. PMID: 37903261
Cobalt-containing alloys are useful for orthopedic applications due to their low volumetric wear rates, corrosion resistance, high mechanical strength, hardness, and fatigue resistance. Unfortunately, these prosthetics release significant levels of...
5.
Shemshaki N, Kan H, Barajaa M, Lebaschi A, Otsuka T, Mishra N, et al.
ACS Biomater Sci Eng . 2023 Sep; 9(10):5782-5792. PMID: 37769114
The high retear rate after a successful repair of the rotator cuff (RC) is a major clinical challenge. Muscle atrophy and fat accumulation of RC muscles over time adversely affect...
6.
Ude C, Dzidotor G, Iloeje K, Nair L, Laurencin C
ACS Appl Bio Mater . 2023 Jun; 6(6):2029-2042. PMID: 37261398
Arthroplasty implants can undergo corrosion at the modular components, trunnion, and hinges, owing to implant material makeup, micromotion, and interaction with body fluid. In this review, various mechanisms of corrosion...
7.
Knight B, Walker J, Nair L
Regen Eng Transl Med . 2022 Oct; 7(3):262-282. PMID: 36275437
The most common disabling symptom of osteoarthritis (OA) is pain. Clinical investigations using disease-specific animal models have increased our insights into the pathophysiology of osteoarthritic pain. As the prevalence of...
8.
Daniels R, Morato E, Yassin O, Mao J, Mutlu Z, Jain M, et al.
ACS Appl Mater Interfaces . 2022 Sep; 14(38):42804-42811. PMID: 36112124
The legalization of hemp cultivation in the United States has caused the price of hemp-derived cannabinoids to decrease 10-fold within 2 years. Cannabidiol (CBD), one of many naturally occurring diols...
9.
Ude C, Shah S, Ogueri K, Nair L, Laurencin C
Regen Eng Transl Med . 2022 Aug; 8(2):210-224. PMID: 35958164
Purpose: The knee joint is prone to osteoarthritis (OA) due to its anatomical position, and several reports have implicated the imbalance between catabolic and anabolic processes within the joint as...
10.
Shemshaki N, Kan H, Barajaa M, Otsuka T, Lebaschi A, Mishra N, et al.
Proc Natl Acad Sci U S A . 2022 Aug; 119(33):e2208106119. PMID: 35939692
Massive rotator cuff tears (MRCTs) of the shoulder cause disability and pain among the adult population. In chronic injuries, the tendon retraction and subsequently the loss of mechanical load lead...