Lakshmanane Premkumar
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Explore the profile of Lakshmanane Premkumar including associated specialties, affiliations and a list of published articles.
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86
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4556
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Recent Articles
1.
Thiono D, Samaras D, Phan T, Zhu D, Shah R, Castillo I, et al.
bioRxiv
. 2025 Feb;
PMID: 39990303
The four-dengue virus (DENV) serotypes cause several hundred million infections annually. Several live-attenuated tetravalent dengue vaccines (LAVs) are at different stages of clinical testing and regulatory approval. A major hurdle...
2.
Hein L, Castillo I, Medina F, Vila F, Segovia-Chumbez B, Munoz-Jordan J, et al.
Lancet Microbe
. 2024 Dec;
6(2):100951.
PMID: 39730005
Background: Serology for dengue viruses (DENV) and Zika virus (ZIKV) has been hindered by antibody cross-reactivity, which limits the utility of these tests for surveillance and assessment of sero-status. Our...
3.
Bos S, Zambrana J, Duarte E, Graber A, Huffaker J, Montenegro C, et al.
Lancet Infect Dis
. 2024 Nov;
25(3):346-356.
PMID: 39489898
Background: Dengue is the most prevalent mosquito-borne viral disease and a major public health problem worldwide. Most primary infections with the four dengue virus serotypes (DENV1-4) are inapparent; nonetheless, whether...
4.
Joseph J, Ylade M, Daag J, Aogo R, Crisostomo M, Mpingabo P, et al.
BMC Infect Dis
. 2024 Sep;
24(1):1042.
PMID: 39333882
Background: SARS-CoV-2, the causative agent of COVID-19, is a betacoronavirus belonging to the same genus as endemic human coronaviruses (hCoVs) OC43 and HKU1 and is distinct from alpha hCoVs 229E...
5.
Seaman W, Keener O, Nanayakkara D, Mollan K, Premkumar L, Cuadra E, et al.
Sci Rep
. 2024 Sep;
14(1):21788.
PMID: 39294156
Oral fluids provide ready detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host responses. This study sought to evaluate relationships between oral virus, oral and systemic anti-SARS-CoV-2-specific antibodies,...
6.
Voss W, Mallory M, Byrne P, Marchioni J, Knudson S, Powers J, et al.
Cell Rep Med
. 2024 Aug;
5(8):101668.
PMID: 39094579
We describe the molecular-level composition of polyclonal immunoglobulin G (IgG) anti-spike antibodies from ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, vaccination, or their combination ("hybrid immunity") at monoclonal...
7.
Mallory M, Munt J, Narowski T, Castillo I, Cuadra E, Pisanic N, et al.
Sci Adv
. 2024 Jun;
10(24):eadi1379.
PMID: 38865463
The recommended COVID-19 booster vaccine uptake is low. At-home lateral flow assay (LFA) antigen tests are widely accepted for detecting infection during the pandemic. Here, we present the feasibility and...
8.
Bos S, Zambrana J, Duarte E, Graber A, Huffaker J, Montenegro C, et al.
medRxiv
. 2024 Apr;
PMID: 38633800
Dengue is the most prevalent mosquito-borne viral disease and a major public health problem worldwide. Most primary infections with the four dengue virus serotypes (DENV1-4) are inapparent; nonetheless, whether the...
9.
Voss W, Mallory M, Byrne P, Marchioni J, Knudson S, Powers J, et al.
bioRxiv
. 2024 Mar;
PMID: 38545622
Highlights: ▪ Infection and vaccination elicit unique IgG antibody profiles at the molecular level▪ Immunological imprinting varies between infection (S2/NTD) and vaccination (RBD)▪ Hybrid immunity maintains the imprint of first...
10.
Ciccone E, Zhu D, Gunderson A, Hawke S, Ajeen R, Lodge E, et al.
Open Forum Infect Dis
. 2024 Jan;
11(1):ofae009.
PMID: 38293246
Few studies have described changes in SARS-CoV-2 antibody levels in response to infection and vaccination at frequent intervals and over extended follow-up periods. The purpose of this study was to...