Labanyamoy Kole
Overview
Explore the profile of Labanyamoy Kole including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
231
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0
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Recent Articles
1.
Yanamandra M, Kole L, Archana Giri , Mitra S
J Immunoassay Immunochem
. 2017 Oct;
38(6):663-674.
PMID: 29035165
Phosphatidylinositol-3 kinase (PI3K) pathway regulates multiple cellular functions involving cell survival, growth, motility proliferation, apoptosis, and adhesion. These are deregulated in various diseases such as cancer, atherosclerosis, and inflammation. PI3Ks...
2.
Kole L, Sarkar M, Deb A, Giri B
Pharmacol Rep
. 2016 Jan;
68(1):144-54.
PMID: 26721366
Background: The thiazolidinedione (TZD) class of peroxisome proliferator-activated receptor gamma (PPAR-γ) ligands are known for their ability to induce adipocyte differentiation, to increase insulin sensitivity including anticancer properties. But, whether...
3.
Yanamandra M, Kole L, Archana Giri , Mitra S
Anal Biochem
. 2014 Jan;
449:132-8.
PMID: 24380788
The phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate the cellular signal transduction pathways involved in cell growth, proliferation, survival, apoptosis, and adhesion. Deregulation of these pathways are common in...
4.
Kole L, Giri B, Manna S, Pal B, Ghosh S
Eur J Pharmacol
. 2010 Dec;
653(1-3):8-15.
PMID: 21147093
Biochanin-A, an isoflavone, existing in red clover, cabbage and alfalfa, has an inhibitory and apoptogenic effect on certain cancer cells. However, the actual mechanism by which this compound inhibits proliferation...
5.
Basu N, Kole L, Basu M, Chakraborty K, Mitra P, Owens I
J Biol Chem
. 2008 Jun;
283(34):23048-61.
PMID: 18556656
Finding rapid, reversible down-regulation of human UDP-glucuronosyltransferases (UGTs) in LS180 cells following curcumin treatment led to the discovery that UGTs require phosphorylation. UGTs, distributed primarily in liver, kidney, and gastrointestinal...
6.
Gomes A, Giri B, Kole L, Saha A, Debnath A, Gomes A
Toxicon
. 2007 Aug;
50(6):835-49.
PMID: 17692879
In our earlier communication, it was reported that Indian toad (Bufo melanostictus) skin extract (TSE) possesses antiproliferative and apoptogenic activity in U937 and K562 cells [Giri et al., 2006. Antiproliferative,...
7.
Basu N, Kole L, Basu M, McDonagh A, Owens I
Biochem Biophys Res Commun
. 2007 Jun;
360(1):7-13.
PMID: 17586469
Finding UDP-glucuronosyltransferases (UGT) require protein kinase C-mediated phosphorylation is important information that allows manipulation of this critical system. UGTs glucuronidate numerous aromatic-like chemicals derived from metabolites, diet, environment and, inadvertently,...
8.
Gong X, Kole L, Iskander K, Jaiswal A
Cancer Res
. 2007 Jun;
67(11):5380-8.
PMID: 17545619
Tumor suppressor p53 is either lost or mutated in several types of cancer. MDM2 interaction with p53 results in ubiquitination and 26S proteasomal degradation of p53. Chronic DNA damage leads...
9.
Das A, Kole L, Wang L, Barrios R, Moorthy B, Jaiswal A
Free Radic Biol Med
. 2006 May;
40(10):1843-56.
PMID: 16678022
NAD(P)H/NRH:quinone oxidoreductases (NQO1 and NQO2) protect against oxidative stress and neoplasia. Cross-breeding of NQO1-/- with NQO2-/- mice generated double-knockout (DKO) mice. DKO mice were born normal yet showed myelogenous hyperplasia...
10.
Basu N, Kole L, Kubota S, Owens I
Drug Metab Dispos
. 2004 Jun;
32(7):768-73.
PMID: 15205394
Although the promising immunosuppressant, mycophenolic acid (MPA), has many desirable properties and is widely prescribed for organ transplant recipients, its high oral dosage requirement is not understood. Whereas previous Northern...