L Van Kaer
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Explore the profile of L Van Kaer including associated specialties, affiliations and a list of published articles.
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77
Citations
3760
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Recent Articles
1.
Ahmad R, Chaturvedi R, Olivares-Villagomez D, Habib T, Asim M, Shivesh P, et al.
Mucosal Immunol
. 2014 Mar;
7(6):1340-53.
PMID: 24670427
Expression of claudin-2, a tight junction protein, is highly upregulated during inflammatory bowel disease (IBD) and, due to its association with epithelial permeability, has been postulated to promote inflammation. Notably,...
2.
Wu W, Shi S, Ljunggren H, Cava A, Van Kaer L, Shi F, et al.
Scand J Immunol
. 2012 Aug;
76(6):559-66.
PMID: 22928727
The differentiation and maintenance of Th17 cells require a unique cytokine milieu and activation of lineage-specific transcription factors. This process appears to be antagonized by the transcription factor T-bet, which...
3.
Wu L, Gabriel C, Parekh V, Van Kaer L
Tissue Antigens
. 2009 Apr;
73(6):535-45.
PMID: 19392798
Invariant natural killer T (iNKT) cells are a subset of T lymphocytes that react with glycolipid antigens presented by the major histocompatibility complex class I-related glycoprotein CD1d. Although iNKT cells...
4.
Miyazaki Y, Iwabuchi K, Iwata D, Miyazaki A, Kon Y, Niino M, et al.
Scand J Immunol
. 2008 Jan;
67(3):230-7.
PMID: 18226013
Diet is one of the important factors that modulate immune responses. In the present study, we have examined the capacity of dietary lipids to modify immune responses in mice and...
5.
Van Kaer L
ScientificWorldJournal
. 2003 Jun;
1:630-2.
PMID: 12805764
More than one million Americans have Type 1 diabetes. This disease--also known as autoimmune or juvenile diabetes--strikes children suddenly, makes them dependent on insulin injections for life, and carries the...
6.
Wilson M, Van Kaer L
Curr Pharm Des
. 2003 Feb;
9(3):201-20.
PMID: 12570826
Natural killer T (NKT) cells are a subset of lymphocytes that express receptors characteristic of conventional T cells together with receptors typically found on natural killer cells. A key feature...
7.
Van Kaer L
Tissue Antigens
. 2002 Oct;
60(1):1-9.
PMID: 12366777
Major histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8-expressing cytotoxic T lymphocytes (CTLs). This antigen recognition system is critically important for immune surveillance against viruses and tumors....
8.
Singh A, Wilson M, Hong S, Olivares-Villagomez D, Du C, Stanic A, et al.
J Exp Med
. 2001 Dec;
194(12):1801-11.
PMID: 11748281
Experimental autoimmune encephalomyelitis (EAE) serves as a prototypic model for T cell-mediated autoimmunity. V(alpha)14 natural killer T (NKT) cells are a subset of T lymphocytes that recognize glycolipid antigens presented...
9.
Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, et al.
J Immunol
. 2001 Nov;
167(10):5928-34.
PMID: 11698470
Malaria, caused by infection with Plasmodium spp., is a life cycle-specific disease that includes liver injury at the erythrocyte stage of the parasite. In this study, we have investigated the...
10.
SPENCE P, Sriram V, Van Kaer L, Hobbs J, Brutkiewicz R
Immunology
. 2001 Oct;
104(2):168-74.
PMID: 11683957
CD1 molecules are cell surface glycoproteins, structurally similar to major histocompatibility complex (MHC) class I molecules. The murine CD1d1 molecule has been shown to be essential for the positive selection...