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L Sottrup-Jensen

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Articles 131
Citations 1859
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Recent Articles
1.
Goulas T, Garcia-Ferrer I, Garcia-Pique S, Sottrup-Jensen L, Gomis-Ruth F
Mol Oral Microbiol . 2014 Jul; 29(6):354-64. PMID: 25052482
α2 -Macroglobulin (α2 M) has many functions in vertebrate physiology. To understand the basis of such functions, high-resolution structural models of its conformations and complexes with interacting partners are required....
2.
Nielsen P, Honberg L, Larsen T, Sperling-Petersena H, Sottrup-Jensen L
Biochem Mol Biol Int . 2009 Oct; 42(4):749-57. PMID: 19856292
Monoclonal and polyclonal antibodies were produced against osteocalcin purified from bovine bone. The antibodies were used for the development of a two-site ELISA. A monoclonal antibody recognising residues 15-49 of...
3.
Christiansen M, Larsen S, Oxvig C, Qin Q, Wagner J, Overgaard M, et al.
Clin Genet . 2004 Mar; 65(1):11-6. PMID: 15032969
The efficiency of six maternal serum markers for Down's syndrome (DS), alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), free beta-hCG, pregnancy-associated plasma protein-A (PAPP-A), the proform of eosinophil major basic...
4.
Laursen L, Overgaard M, Soe R, Boldt H, Sottrup-Jensen L, Giudice L, et al.
FEBS Lett . 2001 Aug; 504(1-2):36-40. PMID: 11522292
Pregnancy-associated plasma protein-A (PAPP-A) has recently been identified as the proteinase responsible for cleavage of insulin-like growth factor binding protein (IGFBP)-4, an inhibitor of IGF action, in several biological fluids....
5.
Boldt H, Overgaard M, Laursen L, Weyer K, Sottrup-Jensen L, Oxvig C
Biochem J . 2001 Aug; 358(Pt 2):359-67. PMID: 11513734
The bioavailability of insulin-like growth factor (IGF)-I and -II is controlled by six IGF-binding proteins (IGFBPs 1-6). Bound IGF is not active, but proteolytic cleavage of the binding protein causes...
6.
Overgaard M, Boldt H, Laursen L, Sottrup-Jensen L, Conover C, Oxvig C
J Biol Chem . 2001 Mar; 276(24):21849-53. PMID: 11264294
A novel metalloproteinase with similarity to pregnancy-associated plasma protein-A (PAPP-A), which we denoted PAPP-A2, has been identified. Through expression in mammalian cells we showed that recombinant PAPP-A2 polypeptide of 1558...
7.
Overgaard M, Haaning J, Boldt H, Olsen I, Laursen L, Christiansen M, et al.
J Biol Chem . 2000 Jul; 275(40):31128-33. PMID: 10913121
Pregnancy-associated plasma protein-A (PAPP-A), originally known from human pregnancy serum, has recently been demonstrated to be a metzincin superfamily metalloproteinase involved in normal and pathological insulin-like growth factor (IGF) physiology....
8.
Thomsen A, Sottrup-Jensen L, Gleich G, Oxvig C
Arch Biochem Biophys . 2000 Jun; 379(1):147-52. PMID: 10864452
The determination by protein chemistry methods of the half-cystine status in human eosinophil peroxidase (EPO) is reported. EPO is two-chained and has a total of 14 half-cystine residues. Cys141 and...
9.
Christiansen M, Oxvig C, Wagner J, Qin Q, Nguyen T, Overgaard M, et al.
Prenat Diagn . 1999 Oct; 19(10):905-10. PMID: 10521813
The proform of eosinophil major basic protein (proMBP), the most abundant protein in the eosinophil specific granule, is synthesized by the placenta and secreted into the maternal circulation, where it...
10.
Overgaard M, Oxvig C, Christiansen M, Lawrence J, Conover C, Gleich G, et al.
Biol Reprod . 1999 Sep; 61(4):1083-9. PMID: 10491647
PAPP-A/proMBP, the complex of pregnancy-associated plasma protein-A (PAPP-A) and the proform of eosinophil major basic protein (proMBP), circulates at increasing levels during pregnancy. The major site of synthesis is the...