J GLIEMANN
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Explore the profile of J GLIEMANN including associated specialties, affiliations and a list of published articles.
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Articles
162
Citations
2949
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Recent Articles
1.
Nykjaer A, Fyfe J, Kozyraki R, Leheste J, Jacobsen C, Nielsen M, et al.
Proc Natl Acad Sci U S A
. 2001 Nov;
98(24):13895-900.
PMID: 11717447
Steroid hormones are central regulators of a variety of biological processes. According to the free hormone hypothesis, steroids enter target cells by passive diffusion. However, recently we demonstrated that 25(OH)...
2.
Nielsen M, Madsen P, Christensen E, Nykjaer A, GLIEMANN J, Kasper D, et al.
EMBO J
. 2001 May;
20(9):2180-90.
PMID: 11331584
Sortilin belongs to a growing family of multiligand type-1 receptors with homology to the yeast receptor Vps10p. Based on structural features and sortilin's intracellular predominance, we have proposed it to...
3.
Jacobsen L, Madsen P, Jacobsen C, Nielsen M, GLIEMANN J, Petersen C
J Biol Chem
. 2001 Apr;
276(25):22788-96.
PMID: 11294867
We previously isolated and sequenced the approximately 250-kDa type 1 receptor sorLA/LR11, a mosaic protein with elements characterizing the Vps10p domain receptor family as well as the low density lipoprotein...
4.
Chan W, Shaw P, Tam S, Jacobsen C, GLIEMANN J, Nielsen M
Biochem Biophys Res Commun
. 2001 Feb;
270(2):453-7.
PMID: 10753646
The type-I ribosome-inactivating protein trichosanthin displays selective cytotoxicity, suggesting specific mechanisms for entry into cells. Here we show that trichosanthin binds specifically to the endocytic receptors LRP and megalin, and...
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6.
Lookene A, Nielsen M, GLIEMANN J, Olivecrona G
Biochem Biophys Res Commun
. 2000 Apr;
271(1):15-21.
PMID: 10777674
The C-terminal domain of lipoprotein lipase (LPL) is involved in several important interactions. To assess its contribution to the binding ability of full-length LPL we have determined kinetic constants using...
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8.
Jensen P, Hager H, Nielsen M, Hojrup P, GLIEMANN J, Jakes R
J Biol Chem
. 1999 Aug;
274(36):25481-9.
PMID: 10464279
alpha-Synuclein has been implicated in the pathogenesis of several neurodegenerative disorders based on the direct linking of missense mutations in alpha-synuclein to autosomal dominant Parkinson's disease and its presence in...
9.
Nielsen M, Jacobsen C, Olivecrona G, GLIEMANN J, Petersen C
J Biol Chem
. 1999 Mar;
274(13):8832-6.
PMID: 10085125
Lipoprotein lipase and the receptor-associated protein (RAP) bind to overlapping sites on the low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor (LRP). We have investigated if lipoprotein lipase interacts with the RAP...
10.
Munck Petersen C, Nielsen M, Jacobsen C, Tauris J, Jacobsen L, GLIEMANN J, et al.
EMBO J
. 1999 Feb;
18(3):595-604.
PMID: 9927419
We recently reported the isolation and sequencing of sortilin, a new putative sorting receptor that binds receptor-associated protein (RAP). The luminal N-terminus of sortilin comprises a consensus sequence for cleavage...