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L Scorrano

Explore the profile of L Scorrano including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 2188
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Recent Articles
1.
Manago A, Leanza L, Carraretto L, Sassi N, Grancara S, Quintana-Cabrera R, et al.
Cell Death Dis . 2015 Oct; 6:e1930. PMID: 26492365
Salinomycin, isolated from Streptomyces albus, displays antimicrobial activity. Recently, a large-scale screening approach identified salinomycin and nigericin as selective apoptosis inducers of cancer stem cells. Growing evidence suggests that salinomycin...
2.
Oettinghaus B, Schulz J, Restelli L, Licci M, Savoia C, Schmidt A, et al.
Cell Death Differ . 2015 Apr; 23(1):18-28. PMID: 25909888
Well-balanced mitochondrial fission and fusion processes are essential for nervous system development. Loss of function of the main mitochondrial fission mediator, dynamin-related protein 1 (Drp1), is lethal early during embryonic...
3.
Marini E, Giampietri C, Petrungaro S, Conti S, Filippini A, Scorrano L, et al.
Cell Death Differ . 2014 Dec; 22(7):1131-43. PMID: 25501600
Components of the death receptor-mediated pathways like caspase-8 have been identified in complexes at intracellular membranes to spatially restrict the processing of local targets. In this study, we report that...
4.
Barbieri E, Scorrano L
Cell Death Differ . 2013 Nov; 20(12):1601-2. PMID: 24212930
No abstract available.
5.
Ramonet D, Perier C, Recasens A, Dehay B, Bove J, Costa V, et al.
Cell Death Differ . 2012 Aug; 20(1):77-85. PMID: 22858546
Mitochondrial complex I dysfunction has long been associated with Parkinson's disease (PD). Recent evidence suggests that mitochondrial involvement in PD may extend beyond a sole respiratory deficit and also include...
6.
Cereghetti G, Costa V, Scorrano L
Cell Death Differ . 2010 May; 17(11):1785-94. PMID: 20489733
During apoptosis, mitochondria lose their membrane potential and undergo fragmentation around the time of release of cytochrome c. Apoptotic fission is at least in part sustained by the translocation of...
7.
Palma C, Falcone S, Pisoni S, Cipolat S, Panzeri C, Pambianco S, et al.
Cell Death Differ . 2010 May; 17(11):1684-96. PMID: 20467441
During myogenic differentiation the short mitochondria of myoblasts change into the extensively elongated network observed in myotubes. The functional relevance and the molecular mechanisms driving the formation of this mitochondrial...
8.
Calore F, Genisset C, Casellato A, Rossato M, Codolo G, Esposti M, et al.
Cell Death Differ . 2010 May; 17(11):1707-16. PMID: 20431599
The vacuolating cytotoxin (VacA) is an important virulence factor of Helicobacter pylori with pleiotropic effects on mammalian cells, including the ability to trigger mitochondria-dependent apoptosis. However, the mechanism by which...
9.
Galluzzi L, Aaronson S, Abrams J, Alnemri E, Andrews D, Baehrecke E, et al.
Cell Death Differ . 2009 Apr; 16(8):1093-107. PMID: 19373242
Cell death is essential for a plethora of physiological processes, and its deregulation characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its mechanisms constitutes a formidable...
10.
Vecchione A, Fassan M, Anesti V, Morrione A, Goldoni S, Baldassarre G, et al.
Oncogene . 2008 Oct; 28(2):257-69. PMID: 18931701
Allelic deletions on human chromosome 12q24 are frequently reported in a variety of malignant neoplasms, indicating the presence of a tumor suppressor gene(s) in this chromosomal region. However, no reasonable...