L Scorrano
Overview
Explore the profile of L Scorrano including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
29
Citations
2188
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Cereghetti G, Stangherlin A, Martins de Brito O, Chang C, Blackstone C, Bernardi P, et al.
Proc Natl Acad Sci U S A
. 2008 Oct;
105(41):15803-8.
PMID: 18838687
Changes in mitochondrial morphology that occur during cell cycle, differentiation, and death are tightly regulated by the balance between fusion and fission processes. Excessive fragmentation can be caused by inhibition...
12.
Hausenloy D, Scorrano L
Clin Pharmacol Ther
. 2007 Sep;
82(4):370-3.
PMID: 17851576
Functional consequences of myocardial or cerebral infarction are the result of excessive cell death. It is patent that preventing cell death is the therapeutic goal in any ischemia-reperfusion setting. Mitochondria...
13.
Pellegrini L, Scorrano L
Cell Death Differ
. 2007 Apr;
14(7):1275-84.
PMID: 17464328
Mitochondria are crucial amplifiers of death signals. They release cytochrome c and other pro-apoptotic factors required to fully activate effector caspases. This release is accompanied by fragmentation of the mitochondrial...
14.
Cereghetti G, Scorrano L
Oncogene
. 2006 Aug;
25(34):4717-24.
PMID: 16892085
Mitochondria integrate apoptotic signalling by releasing cytochrome c and other proapoptotic cofactors needed for activation of effector caspases. Previously overlooked morphological changes, mitochondrial fragmentation and cristae remodelling, emerged as subroutines...
15.
Cipolat S, Scorrano L
Cell Death Differ
. 2006 Jul;
13(11):1833-4.
PMID: 16841090
No abstract available.
16.
Letai A, Scorrano L
Cell Death Differ
. 2006 Jul;
13(8):1245-7.
PMID: 16838033
No abstract available.
17.
Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK
Thomas D, Scorrano L, Putcha G, Korsmeyer S, Ley T
Proc Natl Acad Sci U S A
. 2001 Dec;
98(26):14985-90.
PMID: 11752447
Granzyme B (GzmB) is a serine protease that is used by activated cytotoxic T lymphocytes to induce target cell apoptosis. Although GzmB directly cleaves the Bcl2 family member BID on...
18.
Aifantis I, Gounari F, Scorrano L, Borowski C, von Boehmer H
Nat Immunol
. 2001 Apr;
2(5):403-9.
PMID: 11323693
Pre-T cell antigen receptor (pre-TCR) signaling plays a crucial role in the development of immature T cells. Although certain aspects of proximal pre-TCR signaling have been studied, the intermediate signal...
19.
Mootha V, Wei M, Buttle K, Scorrano L, Panoutsakopoulou V, Mannella C, et al.
EMBO J
. 2001 Feb;
20(4):661-71.
PMID: 11179211
Multiple apoptotic pathways release cytochrome c from the mitochondrial intermembrane space, resulting in the activation of downstream caspases. In vivo activation of Fas (CD95) resulted in increased permeability of the...
20.
Petronilli V, Penzo D, Scorrano L, Bernardi P, Di Lisa F
J Biol Chem
. 2001 Jan;
276(15):12030-4.
PMID: 11134038
We investigated the relationship between opening of the permeability transition pore (PTP), mitochondrial depolarization, cytochrome c release, and occurrence of cell death in rat hepatoma MH1C1 cells. Treatment with arachidonic...