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L Ramanathan

Explore the profile of L Ramanathan including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 970
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11.
Butkiewicz N, Wendel M, Zhang R, Jubin R, Pichardo J, Smith E, et al.
Virology . 1996 Nov; 225(2):328-38. PMID: 8918919
The NS3 proteinase of hepatitis C virus utilizes NS4A as a cofactor for cleavages at four sites (3/4A, 4A/4B, 4B/5A, and 5A/5B) in the nonstructural region of the viral polyprotein....
12.
Cook W, Walter L, Murgolo N, Chou C, Petro M, Zavodny P, et al.
Protein Eng . 1996 Jul; 9(7):623-8. PMID: 8844835
The X-ray crystal structure of a rat monoclonal Fab JES1-39D10, raised against recombinant human interleukin-5, has been determined with the use of molecular replacement techniques and refined at 2.7 A...
13.
Ramanathan L, Das N, Li Q
Biol Trace Elem Res . 1994 Jan; 40(1):59-70. PMID: 7511921
Fish phospholipid liposomes were prepared and used as an artificial membrane system to study factors influencing lipid oxidation. The extent of lipid oxidation was indexed by measuring the amount of...
14.
Ramanathan L, Ingram R, Sullivan L, Greenberg R, Reim R, Trotta P, et al.
Biochemistry . 1993 Apr; 32(14):3549-56. PMID: 7682108
Human interleukin 4 is a highly pleiotropic cytokine secreted by activated T cells that exerts multiple biological effects on B and T lymphocytes and other cell types. Elucidation of structure-function...
15.
Ramanathan L, Das N
Biol Trace Elem Res . 1992 Jul; 34(1):35-44. PMID: 1382520
Divalent metal ions (Fe2+, Cu2+, Zn2+, Ni2+, and Mn2+) induced lipid oxidation in cooked, but not in raw fish. The extent of lipid oxidation, measured by the production of thiobarbituric...
16.
Le H, Seelig G, Syto R, Ramanathan L, Windsor W, Borkowski D, et al.
Biochemistry . 1991 Oct; 30(40):9576-82. PMID: 1911743
Human interleukin 4 is a 129 amino acid lymphokine secreted by activated T cells that exerts pleiotropic biological effects on B and T lymphocytes and other hematopoietic cells. Structure-function relations...
17.
Ramanathan L, Le H, Labdon J, Syto R, Arai N, Nagabhushan T, et al.
Biochim Biophys Acta . 1989 Apr; 1007(3):283-8. PMID: 2784692
Recombinant murine interleukin-4 (muIL-4) expressed in COS-7 monkey kidney cells was purified to homogeneity by sequential CM-Sepharose, Sephadex G-100 chromatography and mono-S FPLC to a specific activity of 6.10(7) units...
18.
Le H, Ramanathan L, Labdon J, Syto R, Arai N, Hoy P, et al.
J Biol Chem . 1988 Aug; 263(22):10817-23. PMID: 3260592
We have purified recombinant human interleukin 4 (huIL-4), formerly named B-cell stimulatory factor-1, from supernatants of COS-7 monkey kidney and L-929 cells transfected with the cDNA for huIL-4. The purified...
19.
Ryan D, Ramanathan L, Iida S, Thomas P, Haniu M, Shively J, et al.
J Biol Chem . 1985 May; 260(10):6385-93. PMID: 3997827
Cytochrome P-450j has been purified to electrophoretic homogeneity from isoniazid-treated adult male rats; and this enzyme appears to be a major protein induced in hepatic microsomes after administration of isoniazid,...
20.
Ryan D, Dixon R, Evans R, Ramanathan L, Thomas P, Wood A, et al.
Arch Biochem Biophys . 1984 Sep; 233(2):636-42. PMID: 6486805
Nine rat hepatic microsomal cytochromes P-450 (P-450a-P-450i) have been purified to electrophoretic homogeneity and assayed as potential catalysts of 15 beta-hydroxylation of 5 alpha-androstane-3 alpha,17 beta-diol-3,17-disulfate in a reconstituted system...