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L R Covey

Explore the profile of L R Covey including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 377
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Recent Articles
11.
Lederman S, Yellin M, Cleary A, Pernis A, Inghirami G, Cohn L, et al.
J Immunol . 1994 Mar; 152(5):2163-71. PMID: 7907632
An important component of T cell help for B lymphocyte differentiation is the contact-dependent signaling mediated by the T cell-B cell activating molecule (T-BAM/CD40-L), an activation-induced surface membrane protein on...
12.
Yellin M, Sippel K, Inghirami G, Covey L, Lee J, Sinning J, et al.
J Immunol . 1994 Jan; 152(2):598-608. PMID: 7506727
The T-BAM/CD40-L molecule on CD4+ T cells interacts with B cell CD40 molecules to deliver contact-dependent signals that drive B cell activation and Ig secretion. Cell surface T-BAM/CD40-L expression is...
13.
Lederman S, Yellin M, Covey L, Cleary A, Callard R, Chess L
Curr Opin Immunol . 1993 Jun; 5(3):439-44. PMID: 7688518
Recently, significant progress had been made in understanding the T-B lymphocyte interactions that control humoral immunity. This review highlights experiments that demonstrate a central role for interactions between T-cell-B-cell-activating molecule...
14.
Ferrier P, Covey L, Li S, Suh H, Malynn B, Blackwell T, et al.
J Exp Med . 1990 Jun; 171(6):1909-18. PMID: 2112584
To further analyze the VDJ recombination defect in lymphoid pre-B cells from mice with severe combined immune deficiency (scid mice), we have assayed the ability of Abelson murine leukemia virus...
15.
Covey L, Ferrier P, Alt F
Int Immunol . 1990 Jan; 2(6):579-83. PMID: 2085492
To elucidate the mechanism of VH to VHDJH joining (VH replacement), we have assayed a pre-B cell line for ability to perform V(D)J recombinase-mediated rearrangement events between an unrearranged VH...
16.
Blackwell T, Malynn B, Pollock R, Ferrier P, Covey L, Fulop G, et al.
EMBO J . 1989 Mar; 8(3):735-42. PMID: 2785917
Consistent with an ordered immunoglobulin (Ig) gene assembly process during precursor (pre-) B cell differentiation, we find that most Abelson murine leukemia virus (A-MuLV)-transformed pre-B cells derived from scid (severe...
17.
Blackwell T, Ferrier P, Malynn B, Pollock R, Covey L, Suh H, et al.
Curr Top Microbiol Immunol . 1989 Jan; 152:85-94. PMID: 2805801
Most Abelson murine leukemia virus (A-MuLV)-transformed cell lines derived from scid (severe combined immune deficient) mice actively rearrange their endogenous immunoglobulin (Ig) heavy (H), but not light (L) chain variable...
18.
Ferrier P, Covey L, Suh H, Winoto A, Hood L, Alt F
Int Immunol . 1989 Jan; 1(1):66-74. PMID: 2562155
To elucidate mechanisms that regulate ordered and tissue-specific assembly of Ig and TCR variable region gene segments, we have introduced a recombination substrate comprised of germline TCR beta V, D,...
19.
Coppock D, Covey L, Straus D
J Cell Physiol . 1980 Oct; 105(1):81-92. PMID: 7000803
PG19 mouse melanoma cells arrest growth when they become confluent in medium containing low concentrations of serum. Under these conditions, insulin does not stimulate DNA synthesis in the mouse melanoma...