L Malspeis
Overview
Explore the profile of L Malspeis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
74
Citations
831
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Supko J, Malspeis L
Int J Oncol
. 2011 May;
7(4):847-54.
PMID: 21552913
Genistein (GEN) has recently generated considerable interest as a potential agent for the prevention and treatment of cancer. The present investigation was undertaken to determine if the concentrations of drug...
2.
Supko J, Garcia-Carbonero R, Puchalski T, Malspeis L
Cancer Chemother Pharmacol
. 2001 Oct;
48(3):202-8.
PMID: 11592341
Purpose: Chloroethylnitrosoureas are among the most widely used chemotherapeutic agents for the treatment of brain tumors. SarCNU (1-(2-chloroethyl)3-sarcosinamide-1-nitrosourea) is an investigational nitrosourea analogue that has shown greater antitumor activity and...
3.
Phillips L, Malspeis L, Tubbs E, Supko J
J Pharm Biomed Anal
. 2000 Aug;
23(2-3):395-402.
PMID: 10933532
Zinc finger motifs have been found to be important in a variety of protein structures including transcription factors and viral nucleocapsid proteins. Recently, it was demonstrated that various aromatic disulfides...
4.
Phillips L, Wolfe T, Malspeis L, Supko J
J Pharm Biomed Anal
. 1998 Oct;
16(8):1301-9.
PMID: 9777604
Breflate is a water soluble prodrug developed to facilitate parenteral administration of the investigational antineoplastic agent brefeldin A (BFA). Previously, using analytical methods based upon reversed-phase high performance liquid chromatography...
5.
Marcantonio D, Panasci L, Hollingshead M, Alley M, Camalier R, Sausville E, et al.
Cancer Res
. 1997 Oct;
57(18):3895-8.
PMID: 9307267
Nitrosoureas are among the most widely used agents used in the treatment of malignant gliomas. Here, the activity of 2-chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) was compared with that of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU), in vivo...
6.
Buckheit Jr R, Hollingshead M, Stinson S, Pallansch L, Roberson J, Decker W, et al.
AIDS Res Hum Retroviruses
. 1997 Jun;
13(9):789-96.
PMID: 9171223
A series of compounds related to oxathiin carboxanilide has been identified as nonnucleoside reverse transcriptase inhibitors (NNRTIs) of HIV-1, and structure-activity relationships have been described (Buckheit RW, et al.: Antimicrob...
7.
Burger A, Kaur G, Hollingshead M, Fischer R, Nagashima K, Malspeis L, et al.
Clin Cancer Res
. 1997 Mar;
3(3):455-63.
PMID: 9815705
The spicamycin analogue KRN5500 (NSC 650426; SPA) is derived from Streptomyces alanosinicus. The unique structure contains a purine, an aminoheptose sugar, glycine, and a tetradecadiene fatty acid. SPA potently inhibits...
8.
Drees M, Dengler W, Roth T, Labonte H, Mayo J, Malspeis L, et al.
Clin Cancer Res
. 1997 Feb;
3(2):273-9.
PMID: 9815683
We have selected a panel of human tumor xenografts for in vitro and in vivo studies that allows an indication of selectivity of action of novel chemotherapeutic agents. We report...
9.
Supko J, Phillips L, Malspeis L
J Chromatogr B Biomed Appl
. 1996 Mar;
677(2):351-62.
PMID: 8704941
A facile, sensitive and highly specific HPLC method for assaying 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) in plasma has been developed. The drug was efficiently isolated from plasma by extraction with tert.-butyl methyl ether....
10.
Sausville E, Duncan K, Senderowicz A, Plowman J, Randazzo P, Kahn R, et al.
Cancer J Sci Am
. 1996 Jan;
2(1):52-8.
PMID: 9166499
Purpose: An empiric in vitro screen of human tumor cell lines found brefeldin A inhibited the growth of immortalized human cell lines, with particular sensitivity to brefeldin in a series...